Drug Class - Nonsteroidal Anti-Inflammatory Agents

Name 2 groups of nonsteroidal anti-inflammatory agents (NSAIDS)?

Name 15 NSAIDS?

Name 4 ophthalmic NSAIDS?

NSAIDs are used to control? (3)

Two examples of inflammatory conditions that NSAIDs treat are?

Ophthalmic NSAIDs are used to? (3)

What 3 properties do nonsteroidal anti-inflammatory agents have?

Analgesic and anti-inflammatory effects are due to inhibition of ______ synthesis.

Antipyretic action is due to _____ and inhibition of prostaglandin synthesis in the CNS.

COX-2 inhibitors (celecoxib, rofecoxib, valdecoxib) may cause less _____ _____.

Contraindication?
Hypersensitivity to ____ is a contraindication for the whole group of NSAIDs. Cross-sensitivity may occur.

Precautions?
Use cautiously in patients with a history of _____ disorders, GI bleeding, and severe hepatic, renal, or cardiovascular disease. Safe use in pregnancy is not established and, in general, should be avoided during the second half of pregnancy.

Interactions?
NSAIDs prolong bleeding time and potentiate the effect of
(6)?

Interactions?
Prolonged use with aspirin may result in (increased, decreased) GI side effects and decreased effectiveness.

Interactions?
NSAIDs may also (increase, decrease) response to diuretics or antihypertesnive therapy.

Interactions?
Which drug negates the cardioprotective benefits of low-dose aspirin?

Which drug does NOT negate the cardioprotective effect of low-dose aspirin?

ASSESSMENT:
Patients who have asthma, allergies, and nasal polyps or who are allergic to _____ are at an increased risk for developing hypersensitivity reactions.

ASSESSMENT:
PAIN: Assess pain and limitation of movement...what 3 characteristics of pain should be noted?

ASSESSMENT:
FEVER: Assess fever and note associated signs. Four signs are?

Lab Test Considerations:
Most NSAIDs prolong bleeding time due to suppressed platelet aggregation and, in large doses, may cause prolonged ___. Monitor periodically in prolonged high-dose therapy to assess for ___ blood loss.

List 3 potential nursing diagnoses?

IMPLEMENTATION:
PO: Administer NSAIDs after ____ or with food or an antacid to minimize gastric irritation.

Instruct patient to take NSAIDs with a full glass of water and to remain in an upright position for ___-___ min after administration.

Caution patient to avoid concurrent use of alcohol with this medication to minimize possible _____ irritation.

Three or more glasses of alcohol per day may increase the risk of ____ bleeding with salicylates or NSAIDs.

Caution patient to avoid taking acetaminophen, salicylates, or NSAIDs concurrently for more than a few days, unless directed by hcp to prevent analgesic ______.

Advise patient on long-term therapy to inform hcp of medication regimen prior to surgery. NSAIDs may need to be _____ prior to surgery.

EVALUATION:
Effectiveness of therapy can be demonstrated by: