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60 Cards in this Set

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Tranylcypromine
(Parnate)
MAOI
Phenelzine
(Nardil)
MAOI
Isocarboxazid
(Marplan)
MAOI
Selegiline
MAOI
Trazadone
(desyrel)
Atypical anti-depressant
5- HT2 blocker
Bupropion
Atypical Anti-depressant
lowers seizure threshold
increased NE and DA
Mirtazpine
(Remeron)
3rd gen heterocyclic
atypical antidepressant
stimulates appetite, sedation
maprotiline
Ludiomil
atypical antidepressant
orthostatic hypotension
phencyclidine
PCP
dissociative anesthetic
blocks 5 HT, DA, and NE uptake
nystagmus
LSD
use haloperidol to block hallucinatory affects
cocaine
central nervous system stimulant
an appetite suppressant
topical anesthetic.
5HT-NE-DA reuptake inhibitor
Amphotericin B
Fungizone
Antifungal
pore-forming via ergosterol binding
Flucytosine
Antifungal
pyrimidine antimetabolite (like 5FU)
used with Amp B or Itraconazole
Ketoconazole
Antifungal
Azole
Gynecomastia
CYP450 inhibitor
fluconazole
antifungal
azole
CAN enter CNS
itraconazole
antifungal
azole
caspofungin
antifungal
echinocandin
use for invasive aspergillus
Griseofulvan
topical antifungal
for dermatophytes
Nystatin
topical antifungal
for candida
miconzole
topical antifungal
Econzole
topical antifungal
clotromizole
topical antifungal
terbinafine
topical antifungal
first line for dermatophyte, esp onychomycosis
inhibits squalene epoxidase
CI: pregancy
pralidoxine
Cholinesterase reactivator
used for organophosphate poisoning
parathion
organophosphate
chloroquine
aralen
anti-malarial
acute attacks, not latent infxn
quinine
quinamm
anti-malarial
cinchonism (N/V, tinnits, vertigo, headahe, blurred vision)
blackwater fever = rare complication
mefloquine
lariam
anti-malarial
pyramethamine
daraprim
antimalarial
blood schizonticide
combined with sulfadiazine for toxo
pyrimethamine + sulfadoxine
fansidar
antimalarial
atovagquone/proguanil
malarone
antimalarial
primaquine
tissue schizonticide
antimalarial
sodium stibogluconate
pentostam
antiprotozoal
for leishmania (inhibs phosphofructokinase rxn)
melarsoprol
mel B
antiprotozoal
for typanpsoma brucei
pentamidine
pentam
antiprotozoal
for trypanosoma brucei
nifurtimox
Lampit
antiprotozoal
for Chagas (T. cruzi)
suramin
antrypol
antiprotozoal
for t brucei (no CNS) and Onchocerca volvulus
paromomycin
Humatin
antiprotozoal, aminoglycoside
for lumenal amebiasis
iodoquinol
diodoquin
antiprotozoal for amebiasis
bethanechol
urecholine
direct cholinomimetic
works on bowel and bladder
carbachol
carbastat
direct cholinomimetic
pilocarpine
pilocar
direct cholinomimetic
glaucoma (crisis), crosses BBB
methacholine
mecholyl
direct cholinomimetic
challenge test for asthma/bronchial hyperreactivity
isoflurophate, echothiphate, parathion
organophosphates
indirect cholinomimetic
physostigmine
eserine
indirect cholinomimetic
used in OD of atropine, phenothiazines, TCAs
can enter the BBB
neostigmine
prostigmin
indirect cholinomimetic
edrophonium
enlon
indirect cholinomimetic
used for dx of MG
pyridostigmine
mestinon
indirect cholinomimetic
long-term MG tx
atropine
cholinergic antagonist
muscarinic antagonist
anti-DUMBBELSS
dry as bone, hot as a hair, red as a beet, blind as a bat, mad as a hatter
scopolamine
cholinergic antagonist
nonselective muscarinic blocker
used for motion sickness
homatropine
cholinergic antagonist
topical for mydriasis and cycloplegia
cyclopentolate
cyclogyl
cholinergic antagonist
topical for mydriasis and cycloplegia
tropicamide
cholinergic antagonist
topical for mydriasis and cycloplegia
tubocurarine
cholinergic antagonist
nondepolarizing neuromuscular blockade
pancuronium
cholinergic antagonist
nondepolarizing neuromuscular blockade
atracurium
cholinergic antagonist
nondepolarizing neuromuscular blockade
vecuronium
cholinergic antagonist
nondepolarizing neuromuscular blockade
succinylcholine
cholinergic antagonist
DEPOLARIZING neuromuscular blocker
rapid intubation
DON'T USE WITH HALOTHANE
nicotine
cholinergic antagonist
ganglionic blocker (initial ganglionic excitation)
hexamethonium
cholinergic antagonist
ganglionic blocker (no initial stimulation)