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12 Cards in this Set
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Ultra-Rapid Onset
Short DOA |
1. Insulin lispro (Humalog)
2. Insulin aspart (Novolog) 3. insulin glulisine (Apidra) |
|
Rapid Onset
Short DOA |
Regular Insulin (crystalline zinc)
|
|
Intermediate Onset
Intermediate DOA |
1. Neutral Protamine Hagedorn*
(phosphate buffer) 2. Lente (acetate buffer) –has been discontinued |
|
Intermediate Onset
Extended DOA |
Insulin glargine (Lantus)
Insulin detemir (Levemir) |
|
1st Generation Sulfonylureas
Used for? |
Tolbutamide (Orinase)
Chlorpropamide (Diabinese) Tolazamide (Tolinase) Acetohexamide (Dymelor) Potent Hypoglycemic agents |
|
2nd Generation Sulfonylureas
how different? |
Glyburide (Micronase)
Glipizide (Glucotrol) Glucotrol XL* Glimepiride (Amaryl) 100x more potent |
|
Meglinitides
-used for |
Repaglinide (Prandin)
Nateglinide (Starlix) Reduce post-prandial glucose |
|
Biguanides
-mech? |
Metformin (Glucophage)
decrease hepatic glucose production -warning lactic acidosis |
|
Alpha Glucosidase Inhibitors
mech? |
Acarbose (Precose)
Miglitol (Glyset) prevent breakdown carbs, delayed glucose absorption |
|
Thiazolidinediones
“glitazones” mech? |
Rosiglitazone (Avandia)
Pioglitazone (Actos) sensitize tissues to insulin, bringing glucose into fat and muscle |
|
Incretin Mimetic Agent
mech? |
Exenatide (Byetta)
-looks like glucose, increase glucose dependant insulin secretion and slow gastric emptying |
|
Amylin agonist
mech? |
Pramlintide (Symlin)
delay gastric emptying |
