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18 Cards in this Set

  • Front
  • Back
What are ecoli?
What are shigella sp?
gram neg rod,gram neg rod
what does macconkey agar do to all gram negs?
Inhibits their growth
Lactose +
E coli,
enterobacter,
klebsiella,
proteus
lac -
shigella, salmonella
What are endogenous infections?
Normal flora getting into a new place
exogenous?
unique strains of bacteria causing disease
What gives you travelers diarrhea?
What is heat labile toxin like?
how does it work?
ETEC
very much like cholera toxin
activates adenylate cyclase
What is Heat stable toxin?
similarity between ls and hs?
stimulates guanylate cyclase
both produce secretory diarrhea
EHEC uses what toxin?
What does this toxin do?
Shiga like toxin
inhibits protein synthesis, causes HUS, and dysentery, destruction of renal cells
Can ecoli ever be b hemolytic
yes
EHEC? animal to human or human to human?
REstaurant?
serotype famous?
Other thing it could be called?
animal to human
Jack in the Box
O157: H7
STEC
What's special about the german outbreak?
two copies of shiga like toxin
sorbitol positive
Higher HUS rates
acquired fimbriae genes from enteroaggregative ecoli
Incubation period of EHEC?
how does it begin?
how long before bloody?
fever, invasion, pus?
2-5 days
watery diarrhea
1-2 days
yes, there are sometimes but less than other more invasive bacteria.
What's a big complication of EHEC?
What happens on a sorbitol macconckey agar with EHEC?
HUS
The EHEC colonies will be less colorful (pretty much clear)
Do you give antibiotics with EHEC HUS?
NO
Shigella
Normal flora?
h antigen?
k antigen?
Virulence factors?
transmission
Not normal flora
NO
no,
Invasion plasmid and shigella toxin (exotoxin)
fecal/oral
Shigellosis
fever?
invades which cells inititially?
usually bloody?
yes fever
M cells
No
S. Dysenteriae
what makes this worse?
are there ulcerations?
How distinguish between ehec
Lots more toxin produced
Yes
Ulcerations