Eicosanoid lecture Flash Cards

Play Memory | Create Card File | Append to Card File
Title: Eicosanoid lecture
Description: Eicosanoid lecture
Number of Cards: 10
Save Count: 0
Author: jennifer.sedor13
Created: 2010-12-13
Tags: eicosanoid lecture
Private No

Save Count represents the number of people who have saved this card set to their flashcard list. Consider this an endorsement!

    • Question
    • Answer
    • Side 3
    • Zileuton
    • 5-LO inhibitor

      Long term maint of asthma control
      Steroid-sparing
    • Zafirlukast
    • CysLT1 Receptor antagonist

      Long term maint of asthma control
      Steroid sparing
      Children
      PO
    • Montelukast
    • CysLT1-R antagonist

      Long term maint of asthma
      Steroid-sparing
      Children, PO
    • Cromolyn
    • Inhibits eicosanoid release
      Asthma
    • Dinoprostone
      -MOA
      -PK
    • Synthetic PGE2

      Vaginal preparation
      Stimulateds contraxn of uterus thru prenancy

      Breaks down collagen network to soften cervix
    • Dinoprostone
      -Uses
    • PGE2 and PGF2a, potent oxytoxic action, terminate preg at any stage, induce labor

      Not used in USA
      Abortion 2nd trimester
    • Dinoprostone
      -AEs
    • Dose limiting AE-V/D/fever, depression of fetal heart rate, bronchoconstrxn
      Primary dysmenorrea w inc synth of PGE2 and PGF2a by endometrium, uterus contraxns, pain
    • Prostacyclin
      (epoprostenol)
    • PGI2
      CV system

      Rx of primary pulmonary HTN as continuous IV

      Prevent platelet agg in dialysis machines
    • Misoprostol
    • Gastric ulcers
      PGE1

      Transposition of great vessels
      Abortion

      CONTRA in pregnancy
    • Latanoprost
    • PGF2a derivative
      Decrease IOP by increase outflow of aqueous humor
      Glaucoma
      Drug interaxn w/Thimerosal