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17 Cards in this Set
- Front
- Back
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what are the most common pituitary tumors?
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non functioning tumors (mass effect --> visual disturbance and anterior pituitary problems)
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what is the most common cause of hyperprolactinemia
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drugs (antidepressants, antiHTN, antipsychotics, GI drugs)
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what is the tx of choice for non functioning pituitary tumors
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surgery, but if its not growing and not Sx, just watch it and see if there is growth after 6 months
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what level indicates prolactinoma?
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> 150 ng/dl
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what is the tx of choice for prolactinomas?
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dopamine agonists (dopamine will inhibit prolactin release)
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what disease is caused by ACTH-omas?
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cushings disease
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what test do you give someone you think has cushings disease?
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24 hr urine free cortisol
dexamethasone suppression test (cushing pt require a lot of dexamethasone to suppress cortisol levels) |
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what disease is caused by inappropriately high levels of GH pre-puberty
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gigantism
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what disease is caused by inappropriately high levels of GH after puberty
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acromegaly
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what tests for acromegaly
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IGF-1 level tests, oral glucose intolerance tests (glucose normally suppresses GH levels)
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what drugs would treat acromegaly
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octreotide or dopamine agonists
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what tumor did Dr. Bailey say was extremely rare
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TSH-omas (they would cause hyperthyroidism) call him if you see one :)
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what would cause a delayed onset of puberty (or hypogonadism)or percocious puberty
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LH-oma
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you suspect you patient is deficient in GH because of their short stature, what tests would you run?
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IGF-1 levels and test their response to the following (arginine, GHRH, insulin - you give them hypoglycemia... they wont be happy but its a test)
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a 16 year old boy comes in because he doesn't think he looks like the other guys at school. He is short for his age. Labs show low levels of testosterone and normal LH levels. What is the cause of his problem
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LH should be high but its not. This is secondary hypogonadism because the gonad are intact but their stimulation is off.
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what is kallmann sydrome?
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deficiency in LH causing secondary hypogonadism
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what is klinfelters syndrome?
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primary hypogonadism because the gonads did not develop correctly since it has XXY chromosomes
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