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10 Cards in this Set
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Tissue repair is the restoration of damaged tissue with:
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Tissue renewal/Regeneration - replaces lost cells with same type cells; function maintained.
Fibrosis/scarring - damaged tissue replaced with connective scar tissue consisting of collagen, function often lost |
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Parenchymal tissue
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Functioning cells of an organ
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What is stromal tissue?
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supporting connective tissues
extracellular matrix Blood vessels nerves |
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How does tissue repair occur?
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Cellular proliferation by mitotic production of new cells; daughter cells are same as original cells
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What controls cell proliferation?
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Cellular proliferation is controlled by mitotic factors called growth factors that bind to surface receptors and initiate mitosis
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What are the 4 major phases of the cell cycle?
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G1 - cell components begin to prepare for division
S (synthesis) - DNA replication G2 - organelles double, cytoplasmic components and cytoskeleton increases, prepare for division M - cellular division, prophase, metaphase, anaphase, telophase and cytokinesis G0 - cell permanently exits cell cycle |
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Name the three division of body tissues.
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Continuously doubling (epithelial)
Stable (skeletal, skeletal muscle) Permanent (central nervous system, neurons) |
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Name three properties of stem cells.
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1. Self-renewal - keep dividing
2. Asymmetric replication - always one daughter cell kept, other cell matures 3. Differential potential (potency) - one cell differentiates to different levels |
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What are the different potencies of stem cells?
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Totipotent - can make all tissue types
Pluripotent - can make cells from a germ layer Multipotent - can make a family of cells, differentiated to a specific line Unipotent - one cell type, specific to one organ |
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What are the properties of embryonic stem cells?
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From early stage embryo
Pluripotent cells from inner mass of blastocyst Can generate multiple cell lines |
