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7 Cards in this Set

  • Front
  • Back
penicillin/ cephalosporins
b-lactamase cleavage of b-lactam ring
aminoglycosides
MODIFICATION via acetylation, adenylation, phosphorylation
vancomycin
D ala replaced w/ D lac. Decreased affinity
chloramphenicol
modification via acetlyation
macrolides
methylation of rRNAnear erythromycin's ribosome-binding site
tetracycline
decreased uptake of increased transport out of cell
sulfonamides
altered enz (bact DHF synthetase), dec uptake, increased PABA syn