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Bethanechol
Cholinomimetic agent
Direct Ach Agonist
Clinical App: Postoperative and neurogenic ileus and uriniary retention
Carbachol
Cholinomimetic agent
Direct Ach Agonist
Clinical App: Glaucoma, pupillary contraction, and relief of intraocular pressure
CARBon copy of acetylcholine
Pilocarpine
Cholinomimetic agent
Direct Ach Agonist
Potent stimulator of sweat, tears, saliva. PILE on the sweat and tears.
Methacholine
Cholinomimetic agent
Direct Ach Agonist
Challenge test for diagnosis of asthma, causes bronchoconstriction
Neostigmine
Cholinomimetic agent
Indirect Ach Agonist (anticholinesterase)
Postoperative and neurogenic ileus and urinary retention, myasthenia gravis, reversal of neuromuscular junction blockade (postoperative)
Pyridostigmine
Cholinomimetic agent
Indirect Ach Agonist
(anticholinesterase)
Gets rid of myasthenia gravis
Edrophonium
Cholinomimetic agent
Indirect Ach Agonist
(anticholinesterase)
Diagnosis of myasthenia gravis (extremely short acting)
Physostigmine
Cholinomimetic Agent
Indirect Ach Agonist (anticholinesterase)
Glaucoma and Phyx's atropine overdose
Echothiophate
Cholinomimetic Agent
Glaucoma
Atropine
Muscarinic Antagonist
produce mydriasis and cycloplegia
Homatropine
muscarinic antagonists
produce mydriasis and cycloplegia
Tropicamide
muscarinic antagonist
produce mydriasis and cycloplegia
Benztropine
muscarinic antagonist
PARKinson's disease - PARK my BENZ
Scopolamine
muscarinic antagonist
CNS - patch behind ear for motion sickness
Ipratropium
muscarinic antagonist
Respiratory: Asthma and COPD
Oxybutynin
muscrinic antagonist
Reduce urgency in mild cystits and reduce bladdy spasms
Glycopyrrolate
muscarinic antagonist
Reduce urgency in mild cystitis and reduce bladder spasms
Methscopolamine
muscrinic antagonist
Peptic Ulcer treatment (decreases stomach acid secretion)
Atropine Side Effects and Contraindications
Side Effects:
Hot as a hare
Dry as a bone
Red as a beet
Blind as a bat
Mad as a hatter
Bloated as a toad
Contraindicated in:
Glaucoma
BPH
GI obstruction
Dementia
Infant with fever
Hexamethonium
Nicotinic Antagonist
Ganglionic blocker. Used in experimental models to prevent vagal reflex responses to changes in blood pressure - eg prevents reflex bradycardia caued by NE. "Put a hex on smokers (nicotine) to help them quit.