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3 Cards in this Set
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What does the enzyme catalase do?
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Catalase catalyzes the decomposition of hydrogen peroxide to water and oxygen.
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What is the role of the protein VacA in H. pylori virulence?
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VacA behaves as a passive urea transporter that is potentially capable of increasing the permeability of the gastric epithelium to urea, thereby creating a favorable environment for H. pylori infectivity.
All H. pylori bacteria contain the gene coding for VacA, but the gene is only expressed in those strains that encode another gene, CagA (cytotoxin associated gene). Strains producing VacA and CagA cause more intense tissue inflammation and induce cytokine production. |
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What percentage of those infected with H. pylori develop peptic ulcer disease?
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10-15%
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