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11 Cards in this Set
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- Back
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Gastrin
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Cell: G
Effects: Increase histamine and gastrin secretion Increase somatostatin (negative reg) Increase differentiation and proliferation of stomach/colon cells Amidated = all of the above Glycine extended = no acid production |
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Cholecystekinin
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Cell: I
Effects: Increase pancreatic growth and bicarb/water secretion Decreases gastric emptying Increases bile secretion |
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Secretin
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Cell: S
Effects: Increases pancreatic bicarb/water secretion Increases CCK secretion Inhibits acid/histamine production |
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Motilin
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Cell: M
Effects: Secreted during the interdigestive phase to stimulate the migrating motor complex **Receptors stimulated by erythromycin |
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GIP/GLP-1
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Cell: K and L
Effects: Increases insulin secretion Decreases acid secretion and gastric emptying when stimulated by sugars in the SI Inhibits glucagon secretion and |
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PYY
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Cell: L
Effects: Secreted into the blood to induce the sensation of satiety; diminished in obese people |
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Somatostatin
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Cell: D
Effects: Decreases gastrin release Decreases insulin secretion |
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Ghrelin
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Cell: X
Effects: Induces sensation of hunger and contractility by binding the hypothalamic-pituitary axis |
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Histamine
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Cell: ECL
Effects: Induces acid secretion when secreted in vesicular and free forms |
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Nitric oxide
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Effects: Vasodilation and relaxation of smooth muscle
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Serotonin
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Cell: ECL
Effects: regulation of intestinal fluid transport, peristalsis Critical for visceral sensation and pain |
