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17 Cards in this Set
- Front
- Back
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What does Gastrin do? Where is it released? What stimulates release?
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1. Stimulates gastric acid release, Stimulates growth of gastric oxyntic gland.
2. Antrum, Duodenum 3. Peptides, Amino Acids, Distention, Vagal stimulation |
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What does CCK do? Where is it released? What stimulates release?
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1. Gall bladder contraction, Pancreatic enzyme secretion, Pancreatic bicarb secretion, Growth of exocrine pancreas, inhibits gastric emptying
2. Duodenum, Jejunum 3. Peptides, AA, Fatty Acids, Acid |
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What does Secretin do? Where is it released? What stimulates release?
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1. Pancreatic bicarb secretion, biliary bicarb secretion, Growth exocrine pancreas, pepsin secretion, inhibits gastric acid secretion, inhibits trophic effect of gastrin
2. Duodenum 3. Acid, Fat |
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What does GIP do? Where is it released? What stimulates release?
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1. Insulin release, Inhibits gastric acid secretion.
2. Duodenum, Jejunum 3. Glucose, AA, FA |
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What do hormone is similar to gastrin?
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CCK
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What does Secretin resemble?
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Glucagon, VIP, GIP, GLP-1, GLP-2
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What do D cells secrete?
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Somatostatin
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What does Somatostatin do?
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Inhibits gastrin release
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What are the three phases of gastric acid secretion?
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Cephalic, Gastric, Intestinal
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How much of the gastric acid secretion is accounted for by each phase?
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Cephalic - 60%
Gastric - 30% Intestinal - 10% |
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What releases Secretin?
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S-cells
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What releases gastrin?
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G-Cells
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What do G-cells secrete?
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Gastrin and Intrinsic Factor
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What is intrinsic factor necessary for? What can result from insufficient IF?
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Absorption of cyanocobalamin (B12) in small intestine. Insufficient IF can cause pernicious anemia due to deficiency in B12.
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What releases Histamine?
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Enterochromaffin-like cells
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What can inhibit histamine effect?
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Prostaglandins - via cAMP inhibition
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What controls "Law of Intestine"?
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Myenteric neuronal activity
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