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17 Cards in this Set
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- Back
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Naproxen
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NSAID: COX-2 Inhibitor. prevents urate crystal phagocytosis.
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Indomethacin
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NSAID: COX-2 Inhibitor. prevents urate crystal phagocytosis.
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Sulindac
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NSAID: COX-2 Inhibitor. prevents urate crystal phagocytosis.
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Oxaprozin
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NSAID: COX-2 Inhibitor. prevents urate crystal phagocytosis.
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Aspirin
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COX Inhibitor - not recommended for acute gout
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Tolmetin
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Not understood. doesn't work for acute gout.
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methylprednisone
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glucocorticoid: stimulates mRNA to synthesize specific proteins and enzymes
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triamcinolone
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glucocorticoid: stimulates mRNA to synthesize specific proteins and enzymes
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prednisone
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glucocorticoid: stimulates mRNA to synthesize specific proteins and enzymes
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Febuxostat
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non purine xanthine oxidase inhibitor
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Allopurinol
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purine xanthine oxidase inhibitor
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oxypurinol
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active metabolite of allopurinol, not FDA approved, but compassionate use allowed
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probenecid
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blocks reabsorption of urate w/in kidneys
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sulfinpyrazone
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blocks reabsorption of urate w/in kidneys
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losartan
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Angiotensin II receptor antagonist, modest uricosuric effects
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pegloticase
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pegylated recombinant uricase, converts uric acid to more water soluble allantoin
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rasburicase
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recombinant uricase, converts uric acid to more water soluble allantoin
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