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46 Cards in this Set
- Front
- Back
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Early congenital syphilis
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1st 2 years of life.
exagerrated response of secondary syphilis. influenza like symptoms, HSM, desquamation on palms and soles |
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Late congenital syphilis
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After 5 years
-frontal bossae -saddle nose -short maxilla -peg shaped upper central incisors -mulberry molars -Higoumeniaka's sign (unilateral enlargement of sterno-clavicular part of clavicle) |
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Hutchinson's triad
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in late congenital syphilis
-teeth=peg shaped upper central incisors -interstitial keratitis -CN8 deafness |
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Zoophilic fungi
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Mental Warty Dog
T. mentagrophytes T. verrucosum M. canis |
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Geophilic fungi
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T. nigra-E. wernieckii
Black Piedra-P. Hortae White Piedra-T. Bergelli |
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M/C cause of tinea manuum and pedis
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1. T. rubrum
2. T. mentagrophytes 3. E. flocossum |
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What flouresces on Wood's lamp?
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Pteridine products
-M. audoinii -M. canis 365 nm, nickel-oxide filter |
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M/C saphrophytic causes of onychomycosis?
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Scopulariopsis
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Tinea capitis Ectothrix
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Cats and Dogs Fight and Growl Sometimes
M. Canis M. Audouinii M. Distortum M. Ferrugineum M. Gypseum |
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Tinea Capitis Endothrix
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Yoko Gave Ringo Two Violins
T. Yaundei T. Gouruilli T. Rubrum T. Tonsurans T. Violaceum |
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Terbinafine inhibits?
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squalene oxidase
-allylamines are -cidal |
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Azoles inhibit?
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lanosterol 14-a demethylase
-static |
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KOH from roof of blister skin M/C
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T. mentagrophytes
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Erythrasma
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Corynebacterium minitussismum
-gram (+) rod Coral red fluorescence-Copro III |
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M/C cause of tinea capitis
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T. tonsurans (U.S.)
M. canis (worldwide) |
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Chronic Mucocutaneous Candidiasis associations
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Adult-assoc. with Thymoma.
APEDED syndrome (AIRE gene) -Hypoparathyroidism m/c endocrine association. |
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Black Widow Spider
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Latrodectus mactan
Toxin=alpha latrotoxin (neurotoxin increases catecholamine release and can mimic acute abdomen) "hour glass on body" |
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Brown recluse spider
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Loxosceles reclusa
Spingomyelinase-D -->severe necrosis |
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Chancroid
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H. ducreyi (Gram - rod)
-kissing ulcers -school of fish pattern on Gram Stain -Tx azithromycin |
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G. inguinale
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C. granulomatis
-painless papules -No LAD -Donovan bodies=bipolar staining bacilli in vacuoles in histiocytes tx=TMP/SMX |
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Ulcer assoc. with M. ulcerans
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"Buruli ulcer"
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2nd line treatment for primary syphilis?
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Doxy 100 mg po bid x 14 days, erythro 500 qid for 14 days
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Late latent > 1 year
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2.4 million units PEN once weekly for three weeks or doxy for 30 days
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False positives for syphilis
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-pregnancy
-SLE -chronic liver disease -IV drug use -advancing age infections, vaccinations possibly |
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Requires thiamine and inositol for growth?
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T. verrucosum
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Black Dot Ringworm
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T. tonsurans
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M/C cause tinea corporis gladiatorum
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T. tonsurans
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45 degree angled, wide branching hypae?
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aspergillus
Septated whereas Zygomeces is not. Aspergillus and zygomyces go into blood vessels |
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Bodies associated with molluscum contagiosum?
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Henderson-Patterson
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Describe Koplick's Spots
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punctate white spots with surrounding erythema in buccal mucosa. Seen in Measles.
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What type of virus is herpes?
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DS enveloped DNA virus
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Describe Forsheimer's spots?
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petechial papule son soft palate seen in Rubella (RNA virus in Toga family)
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Target of Parvovirus B19
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red cell globoside (Group P antigen)
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Describe Nagayama's spots?
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soft paplae red papules seen in Roseola (HHV6)
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Superantigen binds to what?
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Class II MHC and Vb regions of TCR's
(5-25% stimularion versus 0.05% of specific antigens) |
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Enteroviruses are in what family?
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Picorna virus family (ssNaked RNA virus)
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Where does smallpox start?
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starts in face and goes down
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Sacral zoster is associated with what?
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neurogenic bladder
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Hand Foot Mouth is assoc. with wht virus m/c?
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coxsackie a16
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Bed Bug
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Cimex Lenticularis
Hep B association |
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P. acnes produces
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protoporphyrin 9 (abs at 417-432 nm)
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HA MRSA codes for resistance with what?
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SCCmecII codes for multi-drug resistance
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Enterovirus are in what family
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Picorna virus family.
Naked SS RNA |
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Perineal rash in 67% with what febrile dermatoses?
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Kawasaki's
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Treats both type I and II reactions in Leprosy
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Clofazamine
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3 TYPES OF LEISHMANIASIS?
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Mucocutaneous-L. braziliensis
Visceral-m/c L. donovani Cutaneous |