• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

image

PLAY BUTTON

image

PLAY BUTTON

image

Progress

1/56

Click to flip

Card Range To Study

through

56 Cards in this Set

  • Front
  • Back
HPV type in common warts
HPV 2,4
"2 common 4 U"
HPV type in plantar warts
HPV type 1
HPV type in flat warts
HPV 3
HPV in Butcher's warts
HPV 7
HPV in genital warts
HPV 6,11
HHV type for varicella
HHV 3.
-Immune status to varicella doe snot correlate with declining CD4 counts
Kaposi's varicelliform eruption
association of atopic dermatitis with HSV infection
Fetus is most at risk when from onset of maternal varicella?
5d before to 2 d after delivery
Conditions associated with KA's
-Muir Torre (sebaceous neoplasms, GI malignancies (colon adenocancer), KA's
-Gryzbowski (generalized eruptive KA's)
-Ferguson Smith (multiple KA's appear suddenly and do not inolute
Multiple Dermatofirbromas associated with?
SLE,
CML,
organ transplant
Tumors associated with nevus sebaceous
-trichoblastomas
-syringocystadenoma papilliferum
-BCC
Nevus sebaceous of Jadassohn Syndrome
Triad of linear nevus sebaceous, seizures, MR
What cytokines incude Th1 (cytotoxic) response?
IL-12 and IFN-gamma

IFN-gamma can suppress TH2 and TH17 responses
Th2 cells are primarily induced by?
IL-4

Th2 cells secrete IL-4 and IL-10
Macular or lichen amyloidosis is associated with what syndrome?
Sipple syndrome, MEN IIA

AD, Ret mutation. Increased inc. of medullary thyroid ca, parathyroid hyperplasia and pheochromocytoma

(AK or keratin derived amyloid)
Type of amyloid in primary systemic amyloidosis?
AL

-30-40% will have cutaneous involvement, waxy papules on flexural regions, neck, central face, tongue, buccal mucosa
Type of amyloid in nodular amyloidosis?
AL
Name three conditions with AA amyloid deposition?
Secondary amyloidosis
FMF
Muckle-Wells syndrome
Endogenous ochronosis is AR and caused be a defect in homogentisic acid oxidae which prevents what from being degraded beyound homogentisic acid?
Tyrosine and phenylalanine


homogentisic acid deposirs in cartilage, joints
Present in blue tattoos?
Chromium
Cobalt
Present in yellow tattoos?
Cadmium
Present in red tattoos?
Cinnabar
Mercury
Types of minocycline Pigmentation?
I-Blue-black in scars, usually facial (Iron from drug-protein complexes)
II-Blue-gray, nl skin, anterior legs (Iron, FM-not from melanin)
III-Muddy brown in sun exposed areas (melanin present)
Nerve to numb for majority of sole of foot?
Posterior tibial
Syndrome with knuckle pads, PPK, koilonychia, deafness?
Bart Pumphrey
Triad for xanthoma disseminatum?
cutaneous xanthomas
MM xanthomas
Diabetes insipidus
Live vaccines?
BCG, Live Flu, MMR, Varicella, YF, Zoster
HPV E7 protein deactivates what?
Rb
HPV E6 protein degrades what?
p53
Woman's lifetime risk of HPV?
80%
LS and A occurs most commonly in what locations?
Neck, shoulders, wrists
can start as a plaque with follicular plugging
What med can cross-link TNF?
InfliXamab
Triad for Churg Strauss?
Asthma
Eosinophilia
Allergic rhinitis
can have vasculitis, skin lesions in 55%

majority of patients respond to prednisone alone

leukotriene inhibitors can cause Churg Strauss
Recommended frequency of Tb screening for all patients on TNF inhibitors?
Annually
Irreversibly binds to all forms of TNFa?
Infliximab

half life is 10 days, may take 2-6 months to wash out
Binds p40 subunit on Il-12 and Il-23?
Ustekinumab
Loss of what correlates with rituximab resistance?
CD20
ALK-1 is positive in most systemic or primary cutaneous anaplastic large cell lymphomas?
Systemic
Melanocytic marker that is a marker of normal differentiation?
HMB-45
What has increased staining in nephrogenic systemic fbirosis but not in morphea?
CD34

also + in DFSP
Ber-EP4 is positive in what and negative in what?
+ in BCC, - in SCC
Normal kappa/lambda ratio?
2/3 kappa: 1/3 lambda is normal ratio.

10 fold deviation suggests clonal b cell proliferation
Location for Borrelia pseudolymphoma?
earlobes, nipples

Tx-penicillin
Patient with whitish fluorescing organism on woods lamp on eyelashes?
Phthirus Pubis

Treat with vaseline
How to treat a pregnant patient with HIV and syphilis?
desensitize with PCN, then treat
Recessive inheritance, SCC's age 20-40 from flat warts?
EDV

HPV 5,8

Rad therapy contraindicated

EVER1 and EVER2 encode integral membrane proteins to ER, may have role in Zn homeostasis
Do sunscreens work in patients with PCT?
Only physical blockers. Consider Soret band 400-410 nm
Breasts with ulcers and surrounding telangiectasias. Ulcers tend to occur along scars from reduction mammoplasty? Ameboid or retiform purpura
Diffuse Dermal angiomatosis of the Breast

Surrounding telangiectasias are areas of increased blood flow around ischemic areas. Increased HIF (Hypoxia inducible factor) causes increase in VEGF
Urine 3:1 Uro:Copro
PCT
Could see preauricular sclerosis with PCT
Super High ANA in lupus patient, think what?
Infection>Lupus Flare
% of syphilis patients with positive RPR at presentation with chancre?
50%

90% have postive treponemal test
Fevers q4-5 days with bone pain, considr what infection?
B. quintana, trench fever
B. henselae is transmitted from cat to cat by what vector?
Flea
How is cimetidine effective for warts?
Cimetidine downregulates local CD8 response and therefore improves local CD4 response.

Imiquimod increased CD4 Effect as well, immune system shift.

Decreased langerhans cells around warts as they trick immune system into cd8 response
Molluscum makes MC54L protein that binds what?
MC54L protein binds IL-18 and inactivates it-->thereby inactivating the TH1 response
Thick white plaques on toes and hands of patient iwth HIV and neuropathy, diagnosis and treatment?
Crusted scabies
Treate with 3-6 weeks of Qweek permethrin
Ivermectin 200 mcg/kg q 2 weeks