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20 Cards in this Set
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- Back
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RDA Thiamin Male/Female
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Male: 1.2 mg/d
Female: 1.1 mg/d |
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Food sources Thiamin
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Meat (pork)
Legumes Whole and enriched cereals and bread |
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2 Thiamin Supplement forms
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Thiamin Hydrochloride
Thiamin Monocitrate |
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2 forms of Thiamin found in nature
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Plants: Free Thiamin
Animals: TDP/TPP |
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Primary absorption site for Thiamin
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Jejunum
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Phosphorylation site for Thiamin
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Mucosal Cells
|
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Types of transport for Low and High concentrations of Thiamin
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Low: Active/Sodium Dependent
High: Passive Diffusion |
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2 anti-absorption factors for Thiamin
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Thiaminases
Polyphenols |
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Where is Thiamin transported in the body
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~90% in RBC
The rest is bound to Albumin in plasma |
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What form does most Thiamin exist in RBC?
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As TDP (~80%)
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Thiamin --> RBC
Type of transport? |
Facilitated Diffusion
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Thiamin --> Tissues
Type of transport? |
Energy Dependent
|
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Where is half the body's Thiamin stored?
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Skeletal Muscles
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HMP Shunt- Transketolase
Function? |
Essential for the generation of pentoses (for nucleic acid synthesis) and NADPH (for fatty acid synthesis).
|
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Synaptic Functions of Thiamin?
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TPP regulates sodium channels of nerve impulses
|
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How to assess Thiamin intake?
2 ways |
Urinary Excretion
Excretion after load test |
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Beriberi
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Wet, Dry, Acute
Thiamin Deficiency |
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3 general symptoms of Beriberi
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Cardiac Abnormalities
Neurological Gastrointestinal |
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Who is at risk for Beriberi?
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People with diseases that alter absorption of thiamin.
Elderly. |
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prevent thiamin deficiency by
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eating refined, unenriched grain products.
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