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52 Cards in this Set
- Front
- Back
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what is atopic dermatits?
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an inherited tendency to develop allergies to common ingested or inhaled antigens
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where do atopic dermatits lesions present in infants?
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cheeks, extensor aspects of forearms and legs
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itchy papules of lichenified patches on extensor aspects of extremities on kids
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atopic dermatitis
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itchy papules or lichenified patches on popliteal, antecubital and wrist areas in adults
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atopic dermatitis
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what is Dennie's pleat?
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extra fold under lower eye lid in atopic individuals
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lesions around follicular orifices that are located on posterior arms, cheeks and thighs
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keratosis pilaris
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what is primary contact dermatitis
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irritant: due to external irritant that will induce a reaction in any individual
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is prior exposure needed in irritant dermatitis?
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no - not ag-ab mediated
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what is allergic contact dermatitis?
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delayed HS reaction that requires sensitization and is patterned
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one or several acute discrete "coin shpaed" patches on legs and arms
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nummular dermatitis
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what population gets nummular dermatitis?
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males 60-70 and females 20-30s with atopic dermatitis
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what causes xerotic dermatitis
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severe dryness, not enough sebaceous fluid
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what causes statis dermatitis?
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chronic venous insufficiency
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edema, pupura and hemosiderotic stain on medial surface of lower legs bilaterally
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statis dermatitis
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what type of lesion characterizes acute stages of eczema?
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vesicles - superimposed on dermal inflammation and edema - very pruritic
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what type of lesion characterizes subacute eczema?
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erythematous plaques with scales and fissures - hyperkeratosis
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what type of lesion characterizes chronic eczema?
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lichenified plaques
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what is spongiosis?
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intercellular edema
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what causes uticaria?
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often allergic reaction - type 1 HS: release of histamine
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erythematous, edematous, sharply circumscribed pruritic plaques that have predilection for pressure poitns that doesn't last longer than 24 hours
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uticaria
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what changes are seen in uticaria lesions
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increased serous fluid in superficial dermis or deep dermis/subQ = angioedema
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skin becomes raised and inflammed when stroked with a dull object
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dermatographic uticaria
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what causes acne vulgaris?
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propionibacterium ances producing lipases that release Fas from sebum inot the pilosebaceous unit
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what is a comedone?
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primary lesion of acne vulgaris - due to hyperkeratinization and occlusion of the follicle
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what produces a blackhead
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a comedone with obsturction higher in the follicle = open
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what produces a whitehead
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comedone with obstruction lower in the follicle = closed
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which are more serious closed or open comedones?
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closed (whiteheads) because continued production of sebum can cause follicle to rupture causing an inflammatory reaction
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what is acne conglobata?
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coalescence of closed obstructions - can leave disfiguring scars
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what area is involved in rosecae?
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central face
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what is missing in rosecea?
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comedomes!!
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what exacerbates rosecea?
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vasodilators: heat, exercise, hot food/drinks, alcohol, spicy foods
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persistent erythema on the face often with telangiectasia
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roseacea erythematotelangiectatic
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what is the most common type of rosecea?
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papulopustular - resembles acne but lacks comedones
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thickened nasal skin that exhibits papulous sebaceous orifices, pustules, nodules and erythema; can develop rhinophyma
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phymatous rosecea
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erythema, conjuctival irritation, dryness, hordeolum orchalazion
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ocular rosecea
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hard yellow/brown/red papules and nodules on the face
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granulomatous rosacea
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what can cause periorifical papular dermatitis
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strong steroid creams applied to the face, makeup, moisturizers and dental products
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erythematous papules that can be scaly or have pustules around mouth,nose or ears
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periorifical papular dermatitis
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what population gets periorifical papular dermatitis
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more common in women
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what causes chlorance
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heavy occupational exposure to chlorinated hydrocarbons
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open comedones, cysts and nodules in malar, retroaruicular and mandibular regions that is also seen on axilla and scrotum
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chlorance
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cutaneous vascular reaction that gores through phases of erythema, edema, hemorrhage and necrosis
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erythema multiform
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concentric pattern: "target" or "iris"
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erythema multiform
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target or raised, edematous papules distributed acrally - especially palms and soles
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erythema multiform minor
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targets or raised edematous papules distributed acrally with involvement of more or more mucous membranes
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erythema multiform major
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widespread blisters on trunk and face with erythematous or pruritic macules and one or more mucous membrane erosions
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SJS/TEN
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what differentiated SJS from TEN?
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SJS has <10% skin involvment; TEN has 30% skin involvement
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multiple painful bluish red nodules on lower legs in the pretibial area
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erythema nodosum
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histology: septal panniculitis and perivascular inflammation without vascular necrosis
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erythema nodosum
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inflammation and necrosis of blood vessels
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vasculitis
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what is characteristic of the histology of vasculitis?
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neutrophil infiltraiton and fibrinoid necrosis
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how does vasculitis manifest?
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palpable purpura and petichieal rash in extremities (hands and feet)
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