• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

image

PLAY BUTTON

image

PLAY BUTTON

image

Progress

1/30

Click to flip

30 Cards in this Set

  • Front
  • Back
What are the five functions of macrophages?
Ingest antigens, act as APCs, ingest dead or infected white cells, assist in rebuilding tissue after infection, secrete cytokines
Explain phagocytosis
Recognition --> Attachment -->Engulfment in phagosome -->Formation of phagolysosome --> Digestion
Which lymphocytic subset produces antibodies?
B cells
Which lymphocytic subset assists in innate immunity?
NK cells
Which lymphocytic subset assists in other areas of immunity?
Helper T cells
Which lymphocytic subset destroys antigens directly?
Cytotoxic T cells
Define apoptosis
Programmed cell death
How does the thymus aid in immunity?
It is the site where T cells mature
Which white blood cell is the first responder to infection, has a nucleus that contains 3-5 lobes, and is a phagocyte?
Neutrophil
What is an opsonin?
A substance that coats antigens in order to signal phagocytes and other components of the immune system
What proteins increase the affinity between leukocytes and endothelial cells?
Integrins
How does the Cluster of Differentiation system classify cells?
By the surface molecules they display
What occurs in the germinal centers?
Differentiation and proliferation of B cells as well as antibody production
What are the two generative, or primary, lymphoid organs and what is the purpose of each?
Bone marrow--Site of development and maturation for B cells and site of development for T cells
Thymus--Site of maturation for T cells
The production of blood cells is called:
Hematopoiesis
What part of the lymph node contains germinal centers?
Secondary follicle
Which molecules increase the adhesive properties of white blood cells and endothelial cells during chemotaxis?
Selectins
What are the three functions of leukocyte movement?
Transporting phagocytes to sites of infection, Transferring mature lymphocytes from sites of maturation to lymphoid organs, Delivering lymphocytes to sites of infection
Cells move from the peripheral blood into the tissues through:
Diapedesis
What macrophage type is found in bone?
Osteoclasts
What are macrophages called when they reside in neural tissue?
Microglia
Macrophages in the liver are known as:
Kupffer cells
Sinusoidal lining cells are macrophages that reside in the:
Spleen
Which white blood cell type has a "lacy" cytoplasm and a kidney bean-shaped nucleus?
Monocyte/macrophage
Which white blood cell is associated with allergic reactions and parasitic infections?
Eosinophils
Which white blood cell type is the most abundant in circulation and is the first cell to respond to an infection?
Neutrophil
Which cell type differentiates into a plasma cell?
B cell
Which cell type is a CD4+ cell?
Helper T cell
Which cell type is a CD8+ cell?
Cytotoxic T cell
What are the three most numerous cell types, in order from greatest to least, seen in the peripheral blood?
Neutrophils, lymphocytes, monocytes