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3 Cards in this Set
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Clonidine (Catapres)
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centrally acting alpha 2 agonists
-still used occasionally -selective stimulation of CNS alpha 2 receptors -primary indication- hypertension (also used for pain and narcotic withdrawal) -oral, transdermal patch, injection adverse effects: drowsiness/sedation (up to 40%), rebound hypertension (abrupt withdrawal), xerostomia |
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Guanabenz +Guanfacine
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Central alpha 2 agonists
-Clonidine "look alikes" -mostly used to decrease bp |
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Methyldopa
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Central alpha 2 fagonist
-older but similar to clonidine -more side effects -hardly ever used -IV form (methyldopate) also rarely used today |
