inflammation

(glomerulonephritis)
–glomerulopaties manifested by
proteinuria or nephrotic syndrome
–glomerulopaties manifested by an isolated
or predominant hematuria
–glomerulopaties manifested as an acute
nephritic syndrome
–glomerular / kidney laesions in vascular
diseases
–glomerular / kidney laesions in SLE
–chronic glomerulonephritis

Wegener's granulomatosis (positive ANCA GN)
1. necrotizing vasculitis
2. necrotizing granulomas in upper aerodigestive tract
3. necrotizing GN
Goodpasture's syndrome (autoantibodies to the
collagen component of BM glomerulus)
Henoch-Schönlein purpura
bleeding into the skin, GIT
in the kidney image IgA nephropathy affectss joints

Tubulointerstitial nephritis (TIN)
acute pyelonephritis
- ascending
- hematogenous
- xantogranulomatous (organized
abscesses)
chronic pyelonephritis
TIN induced by drugs (interstitial edema)

a. serosa (sepsis…, spont. regression)
– a. infectious (cocci, borelia, TBC)
– a. rheumatica (serofibrinous exsudate with
granulocytes
– a. rheumatoides (

RHEUMATIC FEVER
• INFECTIOUS
ENDOCARDITIS

1) allergic vasculitis
2) polyarteritis nodosa - aneurysm, rosary, various histological
changes in aging, Kawasaki disease - in children, often the
coronary arteries
3) granulomatous inflammation - temporal arteritis (giant
cells, thrombosis), Takayasu (pulseless) disease
4) OTHER
Bőrger disease - DK veins, fibrosis neurovascular bundle,
ischemia, smokers
luetic aortitis - scarring of the media

sialoadenitis
s. autoimmune (Sjögren's syndrome.) - prim (sicca
syndrome), secondary (RA, SLE ...) – apoptosis, epithelial
hyperplasia, debris, fibrosis, inflammatory infiltration
lymfoplazmocytic

exocrine – pancreatitis
endocrine - insulitis