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drugs that inhibit translation and therefore inhibit prokaryotes from dividing and proliferating and called what?
protein synthesis inhibitors
Antibiotics that act on the 50s subunit:
CEC
Chloramphenical
Erythromycin
Clindamycin
Antibiotics that act on the 30s subunit:
Tetracycline
Aminoglycosides
Are Aminoglycosides bacterioSTATIC or bacterioCIDAL?
BACTERIOCIDAL
Antibiotics that cause misreading of the mRNA code, generally only working on aerobic gram negative organisms are what?
Aminoglycosides
Antibiotics that target gram negative and are strongly ototoxic, nephrotoxic and neurotoxic are what?
Aminoglycosides
Aluminum, magnesium, iron and calcium significantly impair absorption of this class of antibiotics?
TETRACYCLINES
Patients should avoid excess sun exposure while taking this class?
Tetracyclines
Pseudotumor cerebri can be promoted by this class of drugs?
Tetracyclines
Antacids, iron, and calcium must be avoided within a two hour timeframe of ingesting this class of drugs?
Tetracyclines
Which antibiotic can cause grey baby syndrome?
Chloramphicol
Antibiotic that is especially effective against aerobes but is bone marrow toxic and can yield fatal aplastic anemia?
Chloramphenicol
MOA of Chloramphicol?
binds 50S and blocks action of peptidyl transferase, enzyme needed to form the peptide bond between two AAs
MOA of Erythromycin?
block translocation
This antibiotic is a macrolides?
Erythromycin
Macrolides are the DOC for what?
mycoplasma pneumoniae
What is the DOC in penicillin allergic patients?
Erythromycin
What is the DOC for anaerobic infections that occur above the diaphragm?
Clindamycin
Non-bacterial cells, including our own cells, fungi, and protozoa are also known as what?
EUKARYOTES
What toxin is a protein synthesis inhibitor in EUKARYOTES?
Diphtheria toxin