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40 Cards in this Set
- Front
- Back
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pathophysiology is the study and...
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diagnosis of disease through the examination of organs, tissues, cells and bodily fluids
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pathos in latin is
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suffering or disease
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physis in latin is...
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nature
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etiologic process is..
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what sets disease in progress or motion
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pathogenesis is..
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mechanism of disease development and how the process evolves
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clinical manifestations are...
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functional consequences of change
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treatment is implied by..
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the etiologic process, pathogenisis and clinical manifestations collectively
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pathogenesis is...
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the sequence of cellular and tissue events occuring from initial contact until expression of disease
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two classifications of disease
I and A |
intrinsic and extrinsic
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intrisic disease is..
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inherited
congenital metabolic degenerateive neoplastic immunologic nutritional deficency psychogenic |
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extrinsic disease is..
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aquired
inanimate or physical infectious agent induced |
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morphology
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fundamental structure or form of cells of tissues
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morphologic changes
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concerned with gross anatomic and macroscopic changes that are chaceteristic of disease
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histology
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study of cells and extracellular matrix of tissues
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lesion
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pathologic or traumatic discontinuity of an organ or tissue
structural changes over time |
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incidence
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is a measure of the risk of developing some new condition within a specified period of time.
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prevalence
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the total number of cases of the disease in the population at a given time, or the total number of cases in the population, divided by the number of individuals in the population.
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morbidity
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illness
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mortality
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death
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natural history
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course of a disease without treatment
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prognosis
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likely outcome of a disease
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cross sectional studies
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simultaneous collection of information
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case control studies
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compare persons known to have a disease or condition
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cohorts
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groups of persons born at same time or share characteristics of interests
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longitudinal studies
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following people over time
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general adaption syndrome
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-stress response controlled by neuroendocrine
-stress can be physiologic or psychologic -adaptation to stressors can be healthy or maladaptive -effective coping systems can mediate stress |
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3 stages of general adaption syndrome
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alarm reactions
resistance exhaustion |
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Clinical Course: Acute
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severe, self limiting (ex: heart attack, strep)
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Clinical Course: Subacute
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intermediate, (ex: bacterial endocarditis look harder to find)
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Clinical Course: Chronic
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not able to cure, severe, can run continuous, (ex: diabetes, hypertension, cancer)
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4 stages of the clinical course
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1. Preclinical stage: exposure, incubation phase
2. Subclinical: not clinically apparent, but may or may not become apparent, prodromal phase--latent 3. Clinical: sign and symptoms apparent 4. Carrier Status: harbors organism (remission), short term or permanent |
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Sequela
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after affects that linger
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Positive feedback
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ex: giving birth, very few, exceeds normal set point range for a good reason
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Maintenance of homeostasis
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brainstem, pituitary gland, reticular formation
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Levels of prevention
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Primary: prevent disease from occuring, wash hands, immunization, health education
Secondary: early detection and treatment, screenings, eye exam Tertiary: prevention of complications, chemo, antibiotics, treatments |
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What is a statement about disease pathogenesis?
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Pharyngitis is caused by Group A hemolytic Streptococcus infection
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Brain stem
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where components are balanced and controlled to maintain homeostasis
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Differential diagnosis
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the possibilities that exist given a particular cluster of signs and symptoms
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Two homeostatic control mechanisms
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Negative feedback: ex: glucose levels
Pos feedback: ex: release of hormones during giving birth |
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Etiologic factors that affect normalcy
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Biologic (salmonella, strep), Physical (burn), Chemical (drug, alcohol), Nutritional excess or deficit, Enviro (radiation), Genetics (gender)
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