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21 Cards in this Set
- Front
- Back
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Lawsonial intracellularis
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gram negative
curved rod aerobe obligate intracellular intestinal tract fecal oral route don't culture |
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Lawsonia intracellularis diseases
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proliferative enteropathy - Piges, foals, hamsters (wet tail)
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Lawsonia intracellularis pathogenesis
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internalization by enterocytes - LsaA - Lawsonia surface antigen
escape into cytoplasm - Type III gets out of phagosome into cyte local intestinal spread |
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Lawsonia intracellularis pathology
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proliferation of enterocytes, edema, hemorrhage, minimal inflammation, proliferative lesions
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Lawsonia intracellularis diagnosis treatment and control
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diagnosis via herd history/clinical signs
treatment: microbials Control: prevent introduction porcine: vaccine |
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Helicobacter general characteristics
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Gram negative
helical curved rods microaerophilic extracellular |
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Helicobacter
environment and transmission |
gastric mucosa, colon, liver, bile ducts, ingestion
ingestion |
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Helicobacter nomenclature
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H. pylori
non-H. pylori helicobacter: |
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Helicobacter diseases
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gastritis, ulceration - various species
Hepatitis |
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Helicobacter zoonosis
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Not H. pylori
possibly other helicobacters human to animal, not animal to human |
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Helicobacter diagnosis/treatment
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DX: culture gastric mucosa, feces, detection of urease - ammonia in breath
TX:metronidazole/ampicillin/pepto |
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H. pylori species
Non-H. pylori species |
Human pathogen
various species associated with animals, may cause gastritis ulceration, may transmit to humans |
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Spirochetes General characteristics
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Brachyspira, Leptospira, Borrelia, Treponema
Gram neg, better with silver flagella b/t cell wall and outer membrane extracellular bacteria |
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Spirochetes flagella in
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periplasmic space
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Brachyspira hyodysenteriae general characteristics
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gram negative
slender helical obligate anaerobes extracellular |
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Brachyspira environment/reservoirs, transmission
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intestinal tract
asymptomatic pigs, rodents, dogs fecal-oral |
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Brachyspira diseases
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B. hyodysenteriae - swine dysentery - severe hemorrrhagic
B. pilosocoli - intesting spirochetosis - mild diarrhea |
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Brachyspira hyodysenteriae pathogenesis
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flagella colonization of colonic crypts
cyotoxins LPS |
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Brachyspira hyodysenteriae may require
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other anaerobes, Fusobacterium, Bacteroides, vulgatus, Bacteroides fragilis
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Brachyspria hyodysenteriae vs B. pilocicoli
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colon vs cecum/colon
bloody mucoid vs watery mucoid grower/feeder vs post-weaning |
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B. hyodysentiae vs L. intracellularis
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Swine dysentery vs Proliferative enteropathy
colon vs ileum gloody, mucoid vs proliferative lesions grower/feeder vs post weaning |
