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78 Cards in this Set
- Front
- Back
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neoplasm
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A localized tumor
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reticulate body
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An intracellular stage in the life cycle of chlamydias
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bunyavirus
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An enveloped RNA virus that causes some forms of respiratory distress and hemorrhagic fever
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parvovirus
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A small, naked DNA Virus
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release
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The exit from the host cell of new virions, which usually kills the host cell
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cell culture
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A culture in the form of a monolayer from dispersed cells and continuous cultures of cell suspensions
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glycoprotein
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A long, spikelike molecule made of carbohydrate and protein that projects beyond the surface of a cell or viral envelope; some viral glycoproteins attach the virus to receptor sites onhost cells, while others aid fusion of viral and cellular membranes
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plaque-forming unit
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A plaque counted on a bacterial lawn that gives only an approximate number of phages present, because a given plaque may have been due to more than one phage
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malignant
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Relating to a tumor that is cancerous
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picornavirus
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A small, naked RNA virus; different genera are responsible for polio, the common cold, and hepatitis
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naked virus
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A virus that lacks an envelope
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latency
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The ability of a virus to remain in host cells for long periods of time while retaining the ability to replicate
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neoplastic transformation
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The uncontrollable divison of host cells caused by infection with a DNA tumor virus
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burst size
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(also called viral yield) The number of new virions released in the replication process
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viroid
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An infectious RNA particle, smaller than a virus and lacking a cuspid, that causes various plant diseases
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hepatovirus
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One of three major groups of picornaviruses that can infect nerve and is responsible for causing hepatitis A
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bacterial lawn
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A uniform layer of bacteria growth on the agar surface in a Petri dish
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oncogene
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A cancer-causing gene
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poxvirus
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DNA virus that is the largest and most complex of all viruses
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negative (-) sense RNA
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An RNA strand made up of bases complementary to those of a positive (+) sense RNA
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latent viral infection
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An infection typical of herpes viruses in which an infection in childhood that is brought under control later in life is reactivated
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lysogenic conversion
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The ability of a prophage to prevent additional infections of the same cell by the same type of phage; also the conversion of a non-toxin-producing bacterium into a toxin-producing one by a temperate phage
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herpes virus
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A relatively large, enveloped DNA virus that can remain latent in host cells for long periods of time
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latent period
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Period of a bacteriophate growth curve that spans the time from penetration through biosynthesis
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burst time
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The time from absorption to release of phages (in the replication process)
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eclipse period
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Period during which viruses have absorbed to and penetrated host cells but cannot be detected in cells
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provirus
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Viral DNA that is incorporated into a host-cell chromosome
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continuous cell line
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Cell culture consisting of cells that can be propagated over many generations
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syncytium
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(plural: syncytia) A multinucleate mass in a cell culture, for example, caused by the respiratory syncytial virus (RSV)
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tumor
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A uncontrolled division of cells, often caused by viral infection
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obligate intracellular parasite
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An organism or virus that can live or multiply only inside a living host cell
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cell strain
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Dominant cell type resulting from subculturing
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hepadnavirus
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A small, enveloped DNA virus with circular DNA; one such virus causes hepatitis B
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TORCH series
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A group of blood tests used to identify teratogenic diseases in pregnant women and newborn infants
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flavivirus
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A small enveloped (+) sense RNA virus that causes a variety of encephalitides, including yellow fever
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spike
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A glycoprotein projection that extends to form the viral capsid or envelope and is used to attach to or fuse with host cells
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adsorption
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The attachment of the virus to the host cell in the replication process
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maturation
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The process by which complete virions are assembled from newly synthesized components in the replication process
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togavirus
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A small, enveloped RNa virus taht multiplies in many mammalian and arthropod cells
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reovirus
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A medium-sized RNA virus that has a double-capsid with no envelope; causes upper respiratory and gastrointestinal infections in humans
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latent disease
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A disease characterized by period of inactivity either before symptoms appear or between attacks
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filovirus
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A filamentious virus that displays unusual variability in shape. Two filoviruses, the Ebola virus and the Marburg virus, have been associated with human disease
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orthomyxovirus
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A medium-sized, enveloped RNA virus that varies in shape from spherical to filamentous and has an affinity for mucus
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penetration
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The entry of the virus (or its nucleic acid) into the host cell in the replication process
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DNA tumor virus
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An animal virus capable of causing tremors
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rheumatoid factor
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IgM found in the blood of patients with rheumatoid arthritis, and their relatives
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R group
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An organic chemical group attached to the central carbon atom in an amino acid
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positive (+) sense RNA
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An RNA strand that encodes information for making proteins needed by a virus
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host range
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The different types of organisms that a microbe can infect
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nucleocapsid
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The nucleic acid and capsid of a virus
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synthesis
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The step of viral replication during which new nucleic acids and viral proteins are made
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replication cycle
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The series of steps of virus replication in a host cell
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monolayer
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A suspension of cells that attach to plastic or glass surfaces as a sheet one cell layer thick
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genome
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The genetic information in an organism or virus
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tissue culture
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Culture made from a single tissue, assuring a reasonably homogenous set of cultures in which to test the effects of a virus or to culture an organism
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papovavirus
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A small, naked DNA virus that causes both benign and malignant warts in humans; some types cause cervical cancer
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capsomere
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A protein aggregate that makes up a viral capsid
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adenovirus
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A medium-sized, naked DNA virus that is highly resistant to chemical agents and often causes respiratory infectinos or diarrhea
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enveloped virus
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A virus with a bilayer membrane outside its capsid
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capsid
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The protein coating of a virus, which protects the nucleic acid core from the environment and usually determines the shape of a virus
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viral specificity
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Refers to the specific types of cells within an organism that a virus can infect
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complex virus
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A virus, such as bacteriophage or poxvirus, that has an envelope or specialized structures
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primary cell culture
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A culture that comes directly from an animal and is not subcultured
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paramyxovirus
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A medium-sized, enveloped RNA virus that has an affinity for mucus
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teratogenesis
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The induction of defects during embryonic development
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enterovirus
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One of three major groups of picornaviruses that can infect nerve and muscle cells, the respiratory tract lining, and skin
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teratogen
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An agent tht induces defects during embryonic development
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cancer
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An uncontrolled, invasive growth of abnormal cells
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virion
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A complete virus particle, including its own envelope if it has one
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envelope
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A bilayer membrane found outside the capsid of some viruses, acquired as the virus buds through one of the host's membrane
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benign
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Not harmful
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subculturing
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The process by which cells from an existing culture are transferred to fresh medium in new containers
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arenavirus
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An enveloped RNA virus that causes Lassa fever and certain other hemorrhagic fevers
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uncoating
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Process in which protein coats of animal viruses that have entered cells are removed by proteolytic enzymes
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plaque essay
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A viral assay used to determine viral yield by culturing viruses on a bacterial lawn and counting plaques
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metastasize
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Relating to the spread of malignant tumors to other body tissues
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plaque
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A clean area in a bacterial lawn culture where viruses have lysed cells`
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cytopathic effect (CPE)
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The visible effect viruses have on cells
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