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86 Cards in this Set

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Describe the respiratory tract's role in EXTERNAL respiration:
carries oxygen to the lungs, and removes carbon dioxide from the lungs.
Describe the respiratory tract's role in INTERNAL respiration:
(aka: cellular respiration)
carries oxygen to body cells where it exchanges with carbon dioxide at the cellular level
Internal & external respiration contribute to maintaining the body's _________ and _________.
pH ; homeostasis
Any deviations from normal:
Anomalies
Respiratory tract ______ produce thick mucus that bathes the upper tract to protect against ________.
secretions ; toxins
Secretions along with ______ prevent pathogens from entering the lower respiratory tract.
cilia
Thick, viscous
tenacious
Secretions collect because of excessive amounts of ________.
mucus
Basic respiratory rhythm and control come form the brain's _________.
medulla
Respiratory system may be affected by ________ controls, but final control is __________.
voluntary ; involuntary
When inadequate oxygen intake results from pathologic respiratory conditions that decrease pulmonary gas exchanges, ________________ is used as a treatment.
oxygen therapy

(ie: COPD)
Because oxygen-carbon dioxide exchange is impaired in individuals with chronic respiratory diseases, carbon dioxide content of the blood tends to ______.
rise
CO2 levels are chronically increased with decreased ______________; due to this the respiratory center of the brain is relatively insensitive to CO2 stimulation, resulting in _________________________.
blood oxygen levels;
decreased involuntary respiratory response
If involuntary respirations are less responsive, usually very low doses of oxygen are prescribed (1-2L/min) to stimulate respirations because larger doses of O2 will _________________________.
further suppress involuntary respirations
Mental confusion, sternal aching or burning, and dry, hacking cough, are all signs of ____________.
O2 toxicity (high O2 levels)
Excessive O2 intake for a long period of time can lead to ________ and _________.
convulsions ; death
The upper respiratory tract consists of the:
nasal cavity, sinuses, pharynx, larynx, trachea, and mouth
Sx's of respiratory tract conditions include:
sneezing, epistaxis, runny nose, dysphonia, itching, and congestion
Inflammation of the nasal mucous membranes:
rhinitis
Allergic rhinitis is caused by _______ release.
histamine
Nonallergic rhinitis is often a sx of __________.
the common cold
Chemical found in body tissue that protects from environmental factors that produce allergic and inflammatory reactions:
histamine
Principal action of histamine is vascular ______ and contraction of ______________ of the bronchial tree and gastrointestinal tract.
dilation ; smooth muscles
Difficulty breathing; subjective sensation of stressful breathing due to respiratory and cardiac exercise or anxiety
dyspnea
Nosebleed:
Epistaxis
Difficulty speaking or hoarseness
Dysphonia
Antihistamines, decongestants, cromolyn, and intranasal glucocorticoids, all may be used to treat:
allergic rhinitis
Decongestants are used to treat:
allergic rhinitis, nonallergic rhinitis, coryza, or the common cold
Inflammation of the mucous membranes of the nose with a profuse nasal discharge:
coryza

commonly called a "head cold"
Hypersecretion of nasal fluids because of allergies may necessitate use of antihistamines in order to block ____________ and to prevent __________ from causing edema, inflammation, and itching.
histamine1 (H1)-receptor sites;
histamine
Antihistamines are most effective if taken ____________.
before contact with allergy-causing compounds.
Antihistamines are not effective against histamines that have already attached to ___________.
receptor sites
Antihistamines are considered _________ because they don't provide protection over a long period of time, and are more likely effective at the beginning of allergy season.
palliative
Alleviating a sx without curing the condition causing the sx:
palliative
Antihistamines fail to reduce the _______ that frequently accompanies seasonal allergic responses such as hay fever.
asthma
True of False?
Tolerance to antihistamine drugs can develop.
True
Histamine can also cause motion sickness, so OTC antihistamines can also relieve sx's such as:
motion sickness, vertigo, hay fever, allergic coughs, allergic rhinitis, and allergies to insect bites and contact dermatitis
Many OTC drugs contain ________ as sleeping aids.
antihistamines
Antihistamines can causing ______ effects and resultant buildup of pressure in the _______.
drying ; eye
Weak, slow body movements caused by lack of muscle coordination or impaired muscle tone
dystonia
Symptoms of motor imbalance and lack of muscle tone:
Extrapyramidal symptoms (effects)
Vasoconstricting agents that shrink the swollen mucous membranes of nasal passages, resulting in decreased nasal drainage, used to relieve nasal congestion:
Decongestants

(come as both oral and nasal preparations)
Patients with hypertension (HTN), hyperthyroidism, diabetes mellitus (DM), or ischemic heart disease are instructed to use OTC ____________ with care.
decongestants
True of False?
Decongestants and Antihistamines must not be combined.
False.

They are often combined.... but care should be taken to keep dosage in safe range.
Decongestants, topical and oral, are for short-term use, with ______________ occurring with just a few days of constant use.
rebound congestion
With topical decongestant nasal agents, the possibility of of rebound congestion becomes _________ as the effect of nasal spray wears off.
greater
Topical decongestants are inappropriate for patients with ________ rhinitis symptoms because discontinuation of topical sprays often produces severe congestion for several days until mucous membranes adjust to lack of medication.
chronic
Due to the danger of rebound congestion, the time limit for topical decongestant use on a regular basis should be ________.
5 days
Relieves allergic rhinitis by preventing release of histamine after allergen exposure
cromolyn sodium (Nasalcrom)

*More effective if used before onset of allergic sx's caused by histamine
*Should be used throughout allergy season bcuz approx. a week is needed to be effective
*Not effective for nonallergic rhinitis
Fluticasone (Flonase) is an example of:
nasal glucocorticoids
Used when prolonged effectiveness for seasonal and perennial allergic rhinitis is needed; suppresses sx's of allergic rhinitis (ie: congestion, rhinorrhea, sneezing, itching, & erythema)
glucocorticoids
(nasal)
Agents that relieve or suppress coughing
antitussives
Agents that block the parasympathetic nerve impulse
Anticholinergic agents
(aka: anticholinergics)
ie: causing dilation of the pupil
Cold-Eeze & Zicam are examples of:
Zinc-based products

*used for common cold sx's
*zinc gluconate glycine (Zicam)
*Zicam: given in forms of dose spoons, nasal sprays, swabs, gels, and tablets that melt in the mouth & may cause loss of smell and taste
A unique blend of herbal extracts, vitamins, electrolytes, and amino acids for a boost to the immune system.
Airborne

*to be used for prophylaxis against the common cold
*effervescent tablet & lozenge forms
Lack of sense of smell:
Anosmia

*caused by zinc-based sprays
Used to suppress cough intensity and frequency while allowing secretions to be eliminated:
Cough preparations
URI:
upper respiratory tract infection
A cough that contains blood expectorated from either the oral cavity or another part of the respiratory tract
hemoptysis
When coughing is prolonged or spastic, __________ may occur
hemoptysis
A _________ cough from COPD should NOT be suppressed.
productive
The 2 major groups of antitussives:
opiod and nonopiod
Group of antitussives that contain hydrocodone, are Schedule III medications, and require a prescription:
opioid cough suppressants
Opioid antitussives that are Schedule V medications that may not require a prescription (based on state laws)
codeine cough suppressants
Codeine suppresses both cough frequency and intensity by elevating the cough __________.
threshold
Codeine preparations can have gastrointestinal side effects, whereas, ___________ do not.
nonopioid cough suppressants
The bronchial tree and lungs make up the __________________.
lower respiratory tract
When lower respiratory tract diseases occur, exchanges of O2 and CO2 cannot occur in the single-layered capillaries of __________, resulting in serious alterations of blood gases.
alveoli
Lower respiratory tract diseases:
List 2 acute conditions...
List 2 chronic conditions...
Acute: pneumonia, acute asthmatic attacks
Chronic: COPD (irreversible), emphysema
Chronic lower respiratory conditions like COPD and emphysema may lead to:
bronchiectasis and atelectasis

*COPD & emphysema also eventually lead to a gas exchange problem resulting in chronic cough, susceptibility to infection, difficulty in engaging in physical activity
An airless condition in the nonexpanded lung
atelectasis
Abnormal condition of bronchial tree characterized by irreversible dilation and destruction of bronchial walls:
bronchiectasis
With lower respiratory diseases, lung damage is irreversible; but palliative relief of sx's is possible via:
bronchodilators and mucolytic agents used along with breathing exercises and O2 therapy
Corticosteroids can reduce the swelling of the _____________.
bronchial tree
A condition caused by an antigen-antibody reaction resulting in wheezing, shortness of breath, and a feeling of suffocation from constriction of bronchioles:
Asthma
During asthmatic attacks, when bronchiole constriction and increased secretions are present, _____________ are used for relief.
bronchodilators
Also used for chronic and acute relief of asthmatic attacks are ____________ agents, such as glucocorticoids and cromolyn.
antiinflammatory
Agent that acts to transmit nerve stimulations in the parasympathetic nervous system; drug that mimics the parasympathetic nervous system:
Cholinergic agents

*(ie: causing constriction of the pupil in the eye)
Pts with chronic respiratory diseases have excessively thick, tenacious sputum that must be thinned for ___________.
expectoration
The act of spitting out saliva or cough materials from the air passages
expectoration
Drugs that react with mucus to make it more watery... thus the cough is more productive, sputum is easier to expectorate, and mucus retention is prevented.
Mucolytics
(aka: mucokinetic agents)
Pt must increase _________ intake when using mucolytics.
fluid
A normal secretion from the mucous membranes of the respiratory tract:
Mucus
An abnormal secretion originating in the lower respiratory tract:
Sputum (mucus & saliva)

*may contain pathologic microorganisms
Agent that decreases the viscosity or thickness of sputum or other secretions of the respiratory tract:
Mucolytics

*They destroy/lyse thick secretions
Renders coughs more productive by stimulating respiratory tract secretions to decrease viscosity of mucus:
Expectorants

*(ie: guaifenesin)