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13 Cards in this Set
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- Back
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What are three examples of "addictions" that can increase bone catabolism?
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1. caffeine
2. tobacco 3. alcohol |
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What is the maximum recommended amount for caffeine intake per day?
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3 drinks/day
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What is the maximum recommended amount for alcohol intake per day?
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2 alcoholic beverages/day
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Are thin or overweight people more susceptible to bone catabolism?
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Thin.
Low BMI and weight loss are factors that increase bone catabolism. |
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What are the 2 critical nutritional components for healthy bones?
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Vitamin D
Calcium |
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What is calcium's role in bone formation?
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It is essential for bone mineralization.
(hydroxyapatite is made of calcium, phosphate, OH) |
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What is the vitamin formed by cholesterol and UV light?
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Vitamin D3 (cholecalciferol)
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What happens to cholecalciferol?
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It is oxidized in the liver to 25-dihydroxycholecalciferol
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What happens to 25-dihydroxycholecalciferol?
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It is oxidized in the kidney to
1,25-dihydroxycholecalciferol aka: 1,25-(OH)2-D3 aka: calcitriol |
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What is calcitriol?
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1. The most active metabolite of vitamin D3.
2. An important calcium regulating hormone |
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What is the action of calcitriol?
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1. Stimulates a calcium binding protein - facilitating calcium transport in gut, bone, kidney.
2. Facilitates phosphate transport |
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How is production of calcitriol regulated?
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1. low Ca/PO4 increases PTH, PTH activates kidney enzyme for calcitriol synthesis
2. high PO4 inhibits synthesis |
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How is one way (nutritionally) that you can get high phosphates (PO4)?
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Drink a lot of pop.
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