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40 Cards in this Set
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Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often around the distal femur, proximal tibial region.
Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
Giant Cell Tumor
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Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often around the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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Occurs most commonly at epiphyseal end of long bones.
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Giant Cell Tumor
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Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often araound the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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Peak incidence 20-40 years old.
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Giant Cell Tumor
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Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often araound the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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Locally aggressive benign tumor often around the distal femur, proximal tibial region.
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Giant Cell Tumor
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Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often araound the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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Characteristic "double bubble" or "soap bubble" appearance on x-ray.
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Giant Cell Tumor
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Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often araound the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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Spindle-shaped cells with multinucleated giant cells
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Giant Cell Tumor
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Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often araound the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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3 Benign primary bone tumors
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Giant Cell Tumor
Osteochondroma (exostosis) Enchondroma |
Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often araound the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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Giant Cell Tumor - occurs where?
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Occurs most commonly at epiphyseal end of long bones.
Locally aggressive benign tumor often around the distal femur, proximal tibial region. |
Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often araound the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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Giant Cell Tumor - peak incidence
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Peak incidence 20-40 years old.
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Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often araound the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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Giant Cell Tumor - appearance on x-ray and histology
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Characteristic "double bubble" or "soap bubble" appearance on x-ray.
Spindle-shaped cells with multinucleated giant cells |
Occurs most commonly at epiphyseal end of long bones. Peak incidence 20-40 years old. Locally aggressive benign tumor often araound the distal femur, proximal tibial region. Characteristic "double bubble" or "soap bubble" appearance on x-ray. Spindle-shaped cells with multinucleated giant cells Benign |
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Most common benign tumor
Usually in men <25 years Commonly originates from long metaphysis Malignant transformation to chondrosarcoma is rare. |
Osteochondroma (exostosis)
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Most common benign tumor Usually in men <25 years Commonly originates from long metaphysis Malignant transformation to chondrosarcoma is rare. |
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Most common benign tumor
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Osteochondroma (exostosis)
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Most common benign tumor Usually in men <25 years Commonly originates from long metaphysis Malignant transformation to chondrosarcoma is rare. |
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Usually in men <25 years
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Osteochondroma (exostosis)
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Most common benign tumor Usually in men <25 years Commonly originates from long metaphysis Malignant transformation to chondrosarcoma is rare. |
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Commonly found metaphysis of long bones
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Osteochondroma (exostosis)
and Osteosarcoma (osteogenic carcinoma) |
Most common benign tumor Usually in men <25 years Commonly originates from long metaphysis Malignant transformation to chondrosarcoma is rare. |
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can rarely transform to malignant chondrosarcoma
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Osteochondroma (exostosis)
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Most common benign tumor Usually in men <25 years Commonly originates from long metaphysis Malignant transformation to chondrosarcoma is rare. |
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Osteochondroma is found in which age groups and gender?
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men < 25 y.o.
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Most common benign tumor Usually in men <25 years Commonly originates from long metaphysis Malignant transformation to chondrosarcoma is rare. |
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Osteochondroma can rarely transform into...
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chondrosarcoma
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Most common benign tumor Usually in men <25 years Commonly originates from long metaphysis Malignant transformation to chondrosarcoma is rare. |
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Osteochondroma often arises where?
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long metaphysis
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Most common benign tumor Usually in men <25 years Commonly originates from long metaphysis Malignant transformation to chondrosarcoma is rare. |
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Benign cartilaginous neoplasm found in intramedullary bone.
Usually distal extremities (vs. chondrosarcoma |
Enchondroma
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Benign cartilaginous neoplasm found in intramedullary bone. |
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Enchondromas are
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Benign cartilaginous neoplasm found in intramedullary bone.
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Benign cartilaginous neoplasm found in intramedullary bone. |
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Enchondromas are often found where?
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Benign cartilaginous neoplasm found in intramedullary bone.
Usually distal extremities |
Benign cartilaginous neoplasm found in intramedullary bone. |
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Name 3 malignant primary bone tumors
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Osteosarcoma (osteogenic carcinoma)
Ewing's sarcoma Chondrosarcoma |
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Most common primary malignant tumor of bone.
Peak incidence in men 10-20 years old. Commonly found in the metaphysis of long bones. Predisposing factors include Paget's disease of bone, bone infarcts, radiation and familial retinoblastoma. Codman's triangle (from elevation of periosteum) on x-ray |
Osteosarcoma (osteogenic carcinoma)
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Most common primary malignant tumor of bone. Peak incidence in men 10-20 years old. Commonly found in the metaphysis of long bones. Predisposing factors include Paget's disease of bone, bone infarcts, radiation and familial retinoblastoma. Codman's triangle (from elevation of periosteum) on x-ray |
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Most common primary malignant tumor of bone.
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Osteosarcoma (osteogenic carcinoma)
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Most common primary malignant tumor of bone. Peak incidence in men 10-20 years old. Commonly found in the metaphysis of long bones. Predisposing factors include Paget's disease of bone, bone infarcts, radiation and familial retinoblastoma. Codman's triangle (from elevation of periosteum) on x-ray |
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Peak incidence in men 10-20 years old.
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Osteosarcoma (osteogenic carcinoma)
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Most common primary malignant tumor of bone. Peak incidence in men 10-20 years old. Commonly found in the metaphysis of long bones. Predisposing factors include Paget's disease of bone, bone infarcts, radiation and familial retinoblastoma. Codman's triangle (from elevation of periosteum) on x-ray |
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Commonly found in the metaphysis of long bones.
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Osteosarcoma (osteogenic carcinoma)
& Osteochondroma (exostosis) |
Most common primary malignant tumor of bone. Peak incidence in men 10-20 years old. Commonly found in the metaphysis of long bones. Predisposing factors include Paget's disease of bone, bone infarcts, radiation and familial retinoblastoma. Codman's triangle (from elevation of periosteum) on x-ray |
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Predisposing factors include Paget's disease of bone, bone infarcts, radiation and familial retinoblastoma.
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Osteosarcoma (osteogenic carcinoma)
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Most common primary malignant tumor of bone. Peak incidence in men 10-20 years old. Commonly found in the metaphysis of long bones. Predisposing factors include Paget's disease of bone, bone infarcts, radiation and familial retinoblastoma. Codman's triangle (from elevation of periosteum) on x-ray |
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Codman's triangle (from elevation of periosteum) on x-ray
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Osteosarcoma (osteogenic carcinoma)
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Most common primary malignant tumor of bone. Peak incidence in men 10-20 years old. Commonly found in the metaphysis of long bones. Predisposing factors include Paget's disease of bone, bone infarcts, radiation and familial retinoblastoma. Codman's triangle (from elevation of periosteum) on x-ray |
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Demographics of Osteosarcoma (osteogenic carcinoma)
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Peak incidence in men 10-20 years old.
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Predisposing factors for Osteosarcoma (osteogenic carcinoma)
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Paget's disease of bone
bone infarcts radiation familial retinoblastoma |
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what does osteosarcoma look like on x-ray?
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Codman's triangle from elevation of periosteum) on x-ray
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Anaplastic small blue cell malignant tumor.
Most common in boys <15 Extrememly aggressive with early mets, but responsive to chemotherapy Characteristic "onion-skin" appearance in bone ("going out for Ewings and onion rings") Commonly appears in diaphysis of long bones, pelvis, scapula, and ribs. 11;22 translocation |
Ewing's sarcoma
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Where does Ewing's commonly appear?
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Commonly appears in diaphysis of long bones, pelvis, scapula, and ribs.
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translocation in Ewings
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11;22 translocation
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Malignant carilaginous tumor
Most common in men aged 30-60 Usually located in pelvis, spine, scapula, humerus, tibia, or femur May be primary origin or from osteochondroma |
chondrosarcoma
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Malignant carilaginous tumor Most common in men aged 30-60 Usually located in pelvis, spine, scapula, humerus, tibia, or femur May be primary origin or from osteochondroma |
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Malignant cartilaginous tumor
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chondrosarcoma
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Malignant carilaginous tumor Most common in men aged 30-60 Usually located in pelvis, spine, scapula, humerus, tibia, or femur May be primary origin or from osteochondroma |
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Most common in men aged 30-60
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chondrosarcoma
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Malignant carilaginous tumor Most common in men aged 30-60 Usually located in pelvis, spine, scapula, humerus, tibia, or femur May be primary origin or from osteochondroma |
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Usually located in pelvis, spine, scapula, humerus, tibia, or femur
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chondrosarcoma
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Malignant carilaginous tumor Most common in men aged 30-60 Usually located in pelvis, spine, scapula, humerus, tibia, or femur May be primary origin or from osteochondroma |
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May be primary origin or from osteochondroma
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chondrosarcoma
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Malignant carilaginous tumor Most common in men aged 30-60 Usually located in pelvis, spine, scapula, humerus, tibia, or femur May be primary origin or from osteochondroma |
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Order of
Diaphysis, Epiphysis, and Metaphysis from ends to middle of bone |
(end) Epiphysis
Metaphysis (middle) Diaphysis |
