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25 Cards in this Set
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- Back
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Imitrex generic and use
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Sumatriptan
Used for migraine/cluster headaches |
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MoA of Sumatriptan
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Selective for serotonin receptors 1B and 1D in cranial arteries causing vasoconstriction and a reduction in inflammation
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Forms and strengths of Imitrex
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Tablets (25mg, 50mg, 100mg);
Injection SUBQ (4mg/0.5mL, 6mg/0.5mL); Nasal spray (5mg, 20mg) |
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Dizziness is more associated with which form of Imitrex
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Injection
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What are some Contraindications for Imitrex?
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Ischemic heart disease, cerebrovascular disease, concurrent use with a MAOI, use of another 5HT agonist within the past 24 hours, uncontrolled hypertension
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What are some adverse effects of the nasal spray form of sumatriptan?
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Bad taste, dizziness, N/V, nasal discomfort
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How are Imitrex tablets administered?
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Take one by mouth at onset of headache and then one every 2 hours if headache persists. Max of 200mg/day
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What are the maximum daily allowances of Imitrex tablets, nasal spray and injection?
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Tablet 200mg/day;
Nasal spray 40mg/day; Injection 2 injections per day at least one hour apart. |
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Does sumatriptan need to be renally dosed? Hepatically dosed?
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It does not need to be renally dosed.
Caution must be used when taken orally if the patient has hepatic impairment. Liver disease will increase its bioavailability. |
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Aceon generic and use
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Perindopril.
Used for hypertension |
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What class of drug is Aceon?
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ACE inhibitor
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What is the MoA of perindopril?
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It works by competitively inhibits ACE, which prevents angiotensin I from becoming angiotensin II preventing vasoconstriction.
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What is/are the forms and strengths of Aceon?
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Tablet (2mg, 4mg, 8mg)
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How is perindopril administered?
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One tablet by mouth daily.
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Does Aceon need to be renally dosed? Hepatically dosed?
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Aceon needs to be dosed renally. CrCl > 30mL/min: 2mg/day starting dose. CrCl < 30mL/min not recommended, use caution
Does not need to be hepatically dosed. |
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What is the maximum daily allowance of perindopril?
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Max of 16mg/day
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What are some common adverse effects associated with Aceon?
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Headache, cough, N/V
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What are some important monitoring parameters for perindopril?
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Serum potassium and serum creatinine; periodic CBC w/diff if the patient has renal impairment and/or collagen vascular disease
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What are some Contraindications for Aceon?
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Hypersensitivity, angioedema associated with previous ACE-i use
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What pregnancy category is Aceon?
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Pregnancy category D
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What is the generic for Azor and its use?
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Amlodipine/Olmesartan
It is used for hypertension |
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What are the MoA for the components in Azor?
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Amlodipine works by inhibiting calcium at "slow channels" or select voltage-sensitive areas of vascular smooth muscle and myocardium
Olmesartan works by selectively and competitively antagonizing the angiotensin II receptor. |
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What pregnancy category is Azor?
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Pregnancy category D
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What are the forms and strengths of Azor?
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Tablet [Amlodipine/Olmesartan] (5mg/20mg, 10mg/20mg, 5mg/40mg, 10mg/40mg)
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How is Azor dosed?
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One tablet by mouth daily.
Start at the lowest dose and titrate up every two weeks until desired effect is reached. Max of 10mg/40mg per day |
