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47 Cards in this Set

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Levothyroxine/Syndthroid
Hormone replacement – synthetic T4
Replaces T4
Thyroid USP/ Armour
Hormone (T3 & T4) from dessicated animal thyroid gland
Replaces both T3 & T4
Liothyronine/Cytomel
Hormone replacement (synthetic T3)
Replaces T3
Propanolol/Inderal
Non-selective beta blocker
Beta 1 & beta 2 receptor blockade
Methimazole/Tapazole
Thionamide
• inhibits transformation of inorganic iodine to organic iodine ‡ blocking thyroxine production
Propylthiouracil/PTU
Thionamide
Inhibits transformation of inorganic iodine to organic iodine‡ blocking production of thyroxine and inhibits coupling of iodotyrosine forming T3 & T4
Iodine/Iodide
Elemental iodine
Large doses inhibit the release of thyroxine
Methysergide/Sansert
ergot derivative
Unknown
Sumatriptan/Imitrex
Serotonin agonist
Serotonin antagonist at 5-HT1d receptors
Omeprazole/Prilosec
Proton pump inhibitor
H+/K+ ATPase proton pump inhibitor
Cimetadine/Tagamet
H2 blocker
Antagonist at H2 receptor
Hyoscyamine/Anaspaz
Anticholinergic
Cholinergic antagonist
Sucralfate/Carafate
Coating agent
Al sucrose polymerizes in acid environment – binds to injured tissue = protective coating
Chlorpromazine/Thorazine
Phenothiazine
D2 dopaminergic receptor site blockade, also H1-histamine and α-adrenergic blockade
Prochlorperazine/Compazine
Phenothiazine
H1-histamine receptor antagonist, also a-adrenergic receptor & D2 dopaminergic receptor antagonist
Respiradone/Risperdal
Benzisoxazole
Unknown,
Haloperidol/Haldol
Butyrophenone
D2 dopaminergic receptor site blockade
Clozapine/Clozaril
Dibenzodiazepine
Multiple receptor site block
Human Growth Hormone/Humatrope
Endocrine – pituitary
Binds to growth hormone receptor on cell‡ formation of other hormones, somatomedins or insulin-like growth factors
Vasopressin (ADH)/Pitressin
Endocrine – pituitary
Stimulate V1 receptors in smooth muscle and V2 receptors in collecting duct
Oxytocin/Pitocin
Endocrine – pituitary
Stimulate specific receptors in myometrium‡ direct muscle contraction and prostaglandin release
Psyllium/Metamucil
GI - laxative
bulk forming, swells in the presence of water, distention stimulates enteric nervous system of gut.
Mg hydroxide/Milk of Magnesia
GI – laxative/cathartic
Osmotic retention in the colon, liquid stool & colon distention
Bisacodyl/Dulcolax
GI – laxative/cathartic
Stimulate intestinal motility and accumulation of electrolytes and water in colon (may inhibit Na/K ATPase)
Diphenoxylate & Atropine/Lomotil
GI – anti diarrheal
1. Opoid
Loperamide/Imodium
GI-Antidiarrheal
Opoid u receptor agonist, decrease motility/secretion
Apomorphine
Emetic
Stimulate CRTZ
Syrup of Ipacac
(CNS) emetic
Stimulate CRTZ, local irritant
Ondansetron/Zofran
Anti emetic
Serotonin antagonist
Chlorpromazine/Thorazine
Anti emetic, anti psychotic
Dopamine antagonist, (anticholinergic, antihistaminic)
Diphenhydramine/Benadryl
Anti histamine, antiemetic
H2 antagonist
Hydrocortisone
Glucocorticoid/corticosteroid
Affects gene transcription - stimulate or repress protein production
Prednisone
Glucocorticoid/corticosteroid
Dexamethasone/Decadron
Glucocorticoid/corticosteroid
Fludrocortisone
Halogenated glucocorticoid/mineralocorticoid agonist
Na is retained by renal tubular cells & not lost in urine
Spironolactone
Mineralocorticoid/aldosterone antagonist, diuretic (K+ sparing)
Competitive binding at aldosterone receptor sites, no binding to DNA
Alendronate/Fosamax
Bisphosphonates
Inhibition of osteoclast activity
Raloxifine/Evista
selective estrogen-receptor modulator (SERM)
• Binding to select estrogen receptor sites.
Calcitonin/Miacalcin
Synthetic hormone
Inhibition of osteoclastic activity
Teriparatide/ Forteo
Synthetic PTH analogue
• Inhibits osteoclast activity.
Testosterone cypionate
Androgenic hormone
• Alteration of gene transcription
Leuprolide/Lupron
Anti-androgenic & anti-estrogenic hormone
Synthetic analong of gonadotropin releasing hormone (GnRH)
Finasteride/Proscar
Anti-androgen
Limits conversion of testosterone to dihydrotestosterone (DHT)
Conjugated estrogens/Premarin
Alters gene transcription
Medroxyprogesterone/Provera
Derivative of progesterone
Alters gene transcription
Insulin Regular
hypoglycemic
Occupies insulin receptors (10% for full fx)
Glucagon
Hyperglycemic
Agonist at glucagons receptors