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53 Cards in this Set

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At what landmark does the internal carotid artery split to form the anterior and middle cerebral arteries?
Anterior Perforated Substance
The pituitary gland and part of the infundibulum are supplied by the______. These are branches of the ___
superior and inferior hypophyseal arteries

ICA (the inferior branch arises in the cavernous sinus, while the superior branch typically arises from the cerebral/supraclinoid part)
The cerebral part of the internal carotid artery gives off what branches?
Superior Hypophyseal Artery
Ophthalmic artery
Posterior communicating artery
Anterior choroidal artery
What artery is critical for visual function?
Central artery of the retina, coming off the opthalmic artery. This artery supplies the optic nerve
The posterior communicating artery travels over the _____
oculomotor nerve
The anterior choroidal artery (AchA) follows the ____in a caudal and lateral direction around the crus cerebri. As it reaches the lateral geniculate body it branches extensively. These branches enter the ______ to supply what?
optic tract

inferior horn of lateral ventricle to supply choroid plexuses
What artery largely supplies the choroid plexuses?
Anterior Choroidal Artery, branching from the Internal Carotid Artery
Hemiplegia, Hemianesthesia, and Hemianopsia are signs consistent with damage to the ___ of the ____. What artery is likely involved?
Posterior Limb of the Internal Capsule.

Anterior Choroidal Artery
The anterior cerebral artery, beyond the anterior communicating artery, supplies what?
the medial aspect of the frontal and parietal lobes
The callosomarginal and pericallosal arteries branch from what artery?
Anterior Cerebral Artery
Stroke patient presents with paralysis of opposite foot and leg, sensory deficits over toes, foot, and leg, cognitive impairments including planning and decision making; loss of initiative, memory and emotional disturbances. What Artery is likely involved?
Anterior Cerebral Artery
The middle cerebral artery moves laterally through the Sylvian cistern, giving off the ______ arteries to the basal ganglia and internal capsule.
lenticulostriate
Branches of the middle cerebral artery on the lateral hemisphere usually include ____, ___, and _____ arteries.
Precentral, Central and Postcentral (Rolandic)
What clinically significant areas are supplied by the middle cerebral artery?
Primary sensory and motor areas for face and arm, speech areas (Broca's and Wernicke's), Parietal Associatin cortex, and frontal eye fields.
What is the clinical presentation for an occulsion of the middle cerebral artery?
Exact presentation will vary depending on which branch is occluded. It may include:
paralysis of opposite face and arm, sensory deficits over opposite face and arm, visual field defects, inattention to opposite side of body, transient paralysis of conjugate gaze to contralateral side.
The posterior cerebral artery travels laterally over the______ and wraps around the ____
oculomotor nerve

Midbrain
The calcarine artery branches off of the ____ artery and supplies the _____
Posterior Cerebral Artery

Primary visual cortex
The PCA supplies the ___, ____ and ____.
Visual Cortex, Temporal Lobe, and part of the thalamus.
Pt presents with hemianopia, alexia (inability to read), and sensory deficits with deep territory involvement. What artery is likely involved?
Posterior Cerebral Artery
PICA supplies the _______and emerges in the cisterna magna where it supplies the _________and then the posterior and medial parts of the________
dorsolateral medulla

choroid plexus of the fourth ventricle

inferior cerebellar surface
The first large branch of the basilar artery is the ____. What does this artery supply?
Anterior Inferior Cerebellar Artery (AICA)

Supplies the ventral and lateral surface of cerebellum, part of the pons, and a little bit of the choroid plexuses in the 4th ventricle.
The anterior groups of the circle of Willis supply what areas?
Optic Chiasm, anterior hypothalamus, anterior perforated substance.
The _______________ supplies the rostral part of the head of the caudate and anterior limb of the internal capsule.
medial striate artery (recurrent artery of Heubner)
The ___________ supply the head and body of the caudate, most of the lenticular nucleus. They also supply the anterior limb, genu, and dorsal posterior limb of the internal capsule.
lateral striate (lenticulostriate) arteries
The________ supply the crus cerebri , the middle and posterior parts of the hypothalamus
posterior perforating groups of the Circle of Willis
The thalamus is supplied primarily by branches of the ______
posterior cerebral artery.
What veins do you find on the lateral surface of the cerebral hermispheres?
Superior anastomotic vein (of Trolard), Inferior Anastomotic vein (of Labbe)
On the base of the brain, the ____ ___and _____ link the cavernous sinus to the transverse sinus and the origin of the internal jugular vein
superior and inferior petrosal sinuses
______ are the major interface for the transport of glucose from blood to neurons. They also act as a reservoir for glycogen.
Astrocytes
Ketone bodies can become an energy source for the brain under what conditions?
neonatal suckling, diabetes, starvation, and low carbohydrate intake.
Metabolism is tightly coupled to cerebral blood flow and produces the basis for ___________. End regulators for metabolism appear to be ___ and ____
functional magnetic imaging.

NO and adenosine
_______ is the most potent regulator of the resistance of cerebral capillary beds
Carbon dioxide partial pressure
The primary anatomical substrates for the blood brain barrier include what?
Tight junctions between capillary endothelial cells

Perivascular cells around capillary endothelial cells

The basement membrane

Astrocytic endfeet that surround cerebral capillaries
A patient develops transient blindness in the right eye that clears after several minutes. What is the most likely cause
emboli in the central retinal artery of the right eye
A patient has valvular heart disease that gives rise to an embolus, which enters the internal carotid artery. What branch of the anterior circulation is it most likely to become lodged?
a middle cerebral artery
The likelihood of stroke arises from both __ and __ factors
modifiable and non modifiable
After a stroke, ____ ___ is reduced within seconds, ___ ___of neurons is inhibited in 2-4 minutes, followed by inhibition of ___ ___
Electrical activity
synaptic excitability
electrical excitability
Normal cerebral blood flow is __ml/100g/min.

There are two primary thresholds associated with a reduction in blood flow, what are they?
55ml/100g/min

at 18ml/100g cells do not function but have potential for recovery

At 8ml/100g/min the threshold of membrane failure is reached and cell death occurs.
Cerebral hemorrhage is usually due to the rupture of small vessels such as the ___ arteries
lenticulostriate
Where do aneurysms normally occur?
at vessel branches
In transient ischemic attacks (TIA’s) sudden neurological deficits occur which, by definition recover before ____ , but usually before ___.
24 hours

10 min
_____ is an example of a TIA which affects the ophthalmic artery, and is an indicator of carotid artery disease.
Amaurosis fugax
Amaurosis fugax is an example of a TIA which affects the ____artery, and is an indicator of _____
ophthalmic

carotid artery disease.
TIA’s in the anterior circulation are most commonly associated with _____,_______sensory or motor dysfunction , or _____ deficits
amaurosis fugax
contralateral (unilateral)
language
In the posterior circulation, TIA’s are associated with____or _____ motor or sensory dysfunction, _____ visual disturbance, ____ numbness, ____, ____, and ____.
bilateral or shifting
bilateral
bifiacial numbness, vertigo, diplopia and ataxia
Watershed strokes occur _____, usually from reduced cerebral blood flow from severe _____ or___. They are usually (bilatera/unilateral)l
along the borders between arterial territories
arterial hypotension or hypoxemia
bilateral
_____ strokes occur along the borders between arterial territories, usually from reduced cerebral blood flow from severe arterial hypotension or hypoxemia. They are usually bilateral
Watershed
Patient has person in a barrel syndrome, with proximal body motor and sensory deficits, expressive language deficits, and behavioral changes. What does this patient have?
Anterior Watershed Infarct (ACA/MCA)
Posterior watershed infarcts (MCA/PCA) can produce ____ and ____ loss and a variety of _____problems
complex visual and sensory
language
Lacunar strokes occur where?
in penetrating arteries to deep tissues of the brain or brainstem (not cortex)
Lacunar strokes are (small/large) and result in cavities from___ - ___ mm in size
small
2-15
The _ artery supplies the rostral part of the head of the caudate and anterior limb of the internal capsule.
The medial striate artery (recurrent artery of Heubner)
The _ arteries supply the head and body of the caudate, most of the lenticular nucleus. They also supply the anterior limb, genu, and dorsal posterior limb of the internal capsule.
lateral striate (lenticulostriate)