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21 Cards in this Set

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MCC primary brain tumor?
- astrocytoma
location of children tumors?
- posterior fossa, infratentorial - btw foramen magum and tentorium cerebrii - contains brainstem and cerebellum
glioblastoma multiforme
- aka grade 4 astrocytoma
- adults , M>F
MCC brain tumor in puberty?
- (astrocytoma?) medulloblastomas, ependymomas, cerebellar or brainstem gliomas
- also optic gliomas, met leukemias
age of onset in meningioma?
- can appear in childhood but symptomatic during adult life
glioma
- broad category that invludes astrocytoma
hyperostosis
- see in bone adjacent to meningioma, also calcification
tumors in pineal region
- astrocytoma, chemodectomas (sympathetic tissue)
- 1/3 germ cell tumors = germinomas, choriocarcinoma
brain tumor in VHL?
- hemangioblastoma often infratentorial
brain met
- #1 lung
- also breast, kidney, skin, uterus
- worst met is skin => bleeds => die
kid with precocious puberty or acromegaly with paroxysms of laughter followed by seizure?
- hypothalamic hamartomas - neoplastic malformation of neurons and glia
craniopharyngiomas
- epithelial neoplasms arising in sella and 3rd ventricle
- hypopit and visual field defects
ependyoma
- tumor arising from ependymal cells (glial cells line ventricles)
- 3rd MC tumor in children
complications of infratentorial tumor?
- transtentorial herniation - upwards herniation across tentorium cerebelli
- transforaminal herniation: downward herniation through foramen magnum
4 y.o. with ataxia and obstructive hydrocephalus
- medulloblastoma
- ataxia 2/2 cerebellum, 4th venctricle obstruction
- ddx: ependymomas (from lining of ventricles => hydroceph)
vestibular schwannomas
- on CN VIII => crushes nerve of choclea
- seen in NF2
parinaud syndrome
- seen in tumors of pineal region
- sx: loss of ertical gaze, pupillary light reflex, lid retraction, convergence, retraction nystagmus
- 2/2 lesion of dorsal midbrain of superior colliculos
pineocytoma
- benign lesion arises from parenchymal cells
- can causes parinaud syndrome
hyperca2+ in neoplasms
- decreased membrane excitability: fatigue, lethargy, wekaness, areflexia
smoker with myasthenia gravis sx, no response to anticholinergics
- lambert eaton myasthenic syndrome
multiple myeloma polyneuropathy
- chronic distal symmetrical sensory loss