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43 Cards in this Set
- Front
- Back
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Vancomycin is used only in _____.
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gram positive infections
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What lab values should be checked before vanco administration?
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blood levels and BUN and creatinine
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Oral vanco is administered when you have _____ _____.
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pseudomembranous colitis
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What is red man syndrome caused by?
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rapid infusion of vanco
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These are broad spectrum antibiotics that suppress bacterial growth by inhibiting protein synthesis.
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tetracyclines
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These are used to treat peptic ulcer disease.
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tetracyclines
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What are tetracycline adverse effects?
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GI irritation, effects of teeth and bones, ototoxicity, hepatotoxicity, renal toxicity
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This drug should not be given to children.
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tetracycline
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What is the oldest member for Macrolides?
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erythromycin
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______ are a safe alternative to PCN.
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Macrolides
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What are some potential drug interactions for macrolides?
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theophylline, warfarin
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This drug is considered one of the safest antibiotics.
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Macrolides
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Aminoglycosides have a _____ therapeutic index.
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narrow
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When using aminoglycosides, you should be careful with the ______.
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kidneys
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____ ____ provide the best way to provide bacterial kill and to minimize ototoxicity or nephrotoxicity.
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Drug levels
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When should the peak be drawn?
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30 minutes after infusion
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How many generations are there of fluroquinolones?
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four
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What can be treated by fluroquinolones?
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UTIs, respiratory infections, anthrax
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Floroquinolones are resistant against _______.
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gonorrhea
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_____ is the agent of choice for postexposure prophylaxis of Bacillus anthracis.
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Fluroquinolones (Cipro)
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Why are patients normally compliant when taking fluroquinolones?
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well absorbed orally and can be administered once or twice a day
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What is a rare adverse effect of fluroquinolones?
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deep tendon rupture
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What is the mechanism of action for sulfonamides?
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Prevents conversion of PABA to folic acid, which is essential for bacterial growth
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How has the development of bacterial resistance to sulfonamides reduced?
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by the use of a combination of a sulfonamide and trimethoprim
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_______ come in a fixed dose combination.
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TMP/SMZ
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What is the primary antibiotic used to treat UTIs?
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TMP/SMZ
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What are adverse side effects of sulfonamides?
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hypersensitivity reactions, Stevens-Johnson syndrome
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What is Stevens-Johnson Syndrome?
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widespread lesions of the skin and mucous membranes, fever, malaise, and toxemia
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_____ turns the urine orange.
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Pyridium
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_____ is used for protozoal infections caused by anaerobic bacteria.
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Flagyl
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This is a new class of drugs used for tx of MRSA and is as effective as vanco.
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oxazolinones
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What type of drug is used for herpes?
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anti-viral
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Vanco does not contain a ___ ____ ____.
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beta lactam ring
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Tetracylcines should not be given to children under ___.
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8
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Macrolides are ___ ____ antibiotics.
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broad spectrum
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True or false. Macrolides should be taken with food.
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False; absorption of certain macrolides is decreased by 50% with food
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Aminoglycosides are extremely _____.
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nephrotoxic
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Aminoglycosides are _____ ____ antibiotics.
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narrow spectrum
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When should the trough be drawn for aminoglycosides?
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just prior to the third dose
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____ is a broad spectrum Floroquinolone used for anthrax.
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Cipro
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What is the most widely used Floroquinolone?
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Cipro
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What is the drug of choice for antibiotic associated colitis caused by C. diff?
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Flagyl (anti-protozoal)
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This drug is widely used as an alternative to PCN.
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Clindamycin
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