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43 Cards in this Set

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  • Back
Vancomycin is used only in _____.
gram positive infections
What lab values should be checked before vanco administration?
blood levels and BUN and creatinine
Oral vanco is administered when you have _____ _____.
pseudomembranous colitis
What is red man syndrome caused by?
rapid infusion of vanco
These are broad spectrum antibiotics that suppress bacterial growth by inhibiting protein synthesis.
tetracyclines
These are used to treat peptic ulcer disease.
tetracyclines
What are tetracycline adverse effects?
GI irritation, effects of teeth and bones, ototoxicity, hepatotoxicity, renal toxicity
This drug should not be given to children.
tetracycline
What is the oldest member for Macrolides?
erythromycin
______ are a safe alternative to PCN.
Macrolides
What are some potential drug interactions for macrolides?
theophylline, warfarin
This drug is considered one of the safest antibiotics.
Macrolides
Aminoglycosides have a _____ therapeutic index.
narrow
When using aminoglycosides, you should be careful with the ______.
kidneys
____ ____ provide the best way to provide bacterial kill and to minimize ototoxicity or nephrotoxicity.
Drug levels
When should the peak be drawn?
30 minutes after infusion
How many generations are there of fluroquinolones?
four
What can be treated by fluroquinolones?
UTIs, respiratory infections, anthrax
Floroquinolones are resistant against _______.
gonorrhea
_____ is the agent of choice for postexposure prophylaxis of Bacillus anthracis.
Fluroquinolones (Cipro)
Why are patients normally compliant when taking fluroquinolones?
well absorbed orally and can be administered once or twice a day
What is a rare adverse effect of fluroquinolones?
deep tendon rupture
What is the mechanism of action for sulfonamides?
Prevents conversion of PABA to folic acid, which is essential for bacterial growth
How has the development of bacterial resistance to sulfonamides reduced?
by the use of a combination of a sulfonamide and trimethoprim
_______ come in a fixed dose combination.
TMP/SMZ
What is the primary antibiotic used to treat UTIs?
TMP/SMZ
What are adverse side effects of sulfonamides?
hypersensitivity reactions, Stevens-Johnson syndrome
What is Stevens-Johnson Syndrome?
widespread lesions of the skin and mucous membranes, fever, malaise, and toxemia
_____ turns the urine orange.
Pyridium
_____ is used for protozoal infections caused by anaerobic bacteria.
Flagyl
This is a new class of drugs used for tx of MRSA and is as effective as vanco.
oxazolinones
What type of drug is used for herpes?
anti-viral
Vanco does not contain a ___ ____ ____.
beta lactam ring
Tetracylcines should not be given to children under ___.
8
Macrolides are ___ ____ antibiotics.
broad spectrum
True or false. Macrolides should be taken with food.
False; absorption of certain macrolides is decreased by 50% with food
Aminoglycosides are extremely _____.
nephrotoxic
Aminoglycosides are _____ ____ antibiotics.
narrow spectrum
When should the trough be drawn for aminoglycosides?
just prior to the third dose
____ is a broad spectrum Floroquinolone used for anthrax.
Cipro
What is the most widely used Floroquinolone?
Cipro
What is the drug of choice for antibiotic associated colitis caused by C. diff?
Flagyl (anti-protozoal)
This drug is widely used as an alternative to PCN.
Clindamycin