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14 Cards in this Set

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What are the 2 general classifications of diseases related to thyroid gland?
functional (hyper or hypothyroidism)
structural (anatomical changes, nodules, enlargement)
Can a physician learn all they need to know from a nm scan to do a proper diagnosis of a thyroid condition?
no they must integrate the findings from the clinical exam, lab results and the nm procedures
What is the patient prep for a thyroid scan?
no medications thyroid hormones and anti-thyroid agents and no food containing iodine
When thyroid tissue migrates to other than the usual location it is called ________ thyroid
When thyroid tissue migrates to other than the usual location it is called lingual thyroid
What is the formula for measuring thyroid uptake before doing scan?
pt count - bkgrd/capsule count-bkgrd x100

what is the normal value?
10-35% for 24 hrs and 6-18% for 4 hrs
What is the thyroid updake with the following data:
thyroid count=56,528
background=367
std capsule=1,284,766
room background=105
24 hr decay factor=.284
56,528-367/(1,284,766 x .284) - 105 x 100
15%
When imaging thyroid with Tc99m pertechnetate how much is the dose, what is the imaging time?
2-10 mCi, 15-30 min post inj, 100-200k counts or 5 min
what is the disadvantage of using Tc compared to I-123?
Tc localizes in the iodine trapping mechanism of the acinar cell and does not give information about organification, storage, or or hormone release functions of the thyroid gland
What is the protocol for imaging with I-123
pt given 100 or 200 microcurie capsule, can image at 4-6 hrs but usually at 24 hrs
What is stunning?
with I-131 a decrease in radioiodine uptake by residual thyroid and/or metastatic thyroid carcinoma following the administration of scanning doses greater than 2 mCi
list 4 main properties seen in a normal thyroid scan
1. homogenous uptake of radiopharmaceutical with well defined borders.
2. each lobe is ellipsoidal in shape with lateral margins typically convex.
3. the isthmus is variable and typically not prominent in adults.
4. a paramidal lobe can be visualized in approximately 1/5 normal pts, commonly seen in graves disease
Elevated levels of plasma thyroid hormones, goiters, graves disease, toxic anenoma, TSH secretion are indications of what condition?
hyperthyroidism
what would be uptake values after 6hrs, 24 hrs?
6hrs - 85%
24hrs - 70%
What is the condition when the following exist: diminished thyroid hormone, increased serum levels of TSH, decreased serum levels of T3 and T4
hypothyroidism

what can this cause?
Thyroiditis, autoimmune (Hashimotos) enlargement to compensate for impaired homonogenesis
True of false: most thyroid nodules are benign?
True, most cancers present as a single or dominant nodule, multiple nodules decrease the likelihood of cancer
list some errors that can occur in thyroid imaging
1. variations in distance from neck to detector.
2. inappropiate neck phantom
3. improper centering of probe over patient's neck
4. background variation or radiation in adjacent areas
5. recent administration or other nuclides