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10 Cards in this Set
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- Back
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Morphine
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Strong Full Agonist
MS Contin, Kadian High affinity for Mu receptor |
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Hydromorphone
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Strong Full Agonist
Dilaudid |
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Oxycodone
|
Strong Full Agonist
Oxycontin |
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Methadone
|
Dolophine
Strong Full Agonist Most often used to treat addiction, sometimes used for severe pain NMDA antagonist and blocks SERT and NET T 1/2 = 8-59 hours. |
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Fentanyl
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Duragesic, Sublimaze
Strong Full Agonist |
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Levorphanol
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Levo Dromoran
Strong Full Agonist T 1/2 = 12-15 hours May block NMDA receptor Used in neuropathic pain. |
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Meperidine
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Demerol
Strong Full Agonist Less potent than morphine. Rapid onset, short duration. (T1/2 = 3 hours) Neurotoxic metabolite - normeperidine that is not reversed by naloxone! |
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Hydrocodone
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Vicodin, Lortab, Lorcet
Mild to Moderate Full Agonist In combo with APAP (N-acetyl-para-aminophenol) |
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Codeine
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Weak Mu receptor agonist
Low analgesic potency, low ceiling. Possess anti-tussive activity. |
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Propoxyphene
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Darvon, Darvon N, Darvocet
Mild to Moderate Full Agonist Low analgesic activity (1/2 as potent as codeine) Neurotoxic metabolite - norpropoxyphene |
