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65 Cards in this Set
- Front
- Back
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What is the adult equivalent of juvenile idiopathic arthritis?
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RA
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What is the incidence of arthritis in children?
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2.2/1000
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How is juvenile idiopathic arthritis classified?
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-Onset at age <16
-Duration >=6 weeks -Exclusion of other arthritis |
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What is the diagnostic test for juvenile idiopathic arthritis?
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NONE
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What are 2 features of osteomyelitis and what investigations are/are not helpful?
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Fever and pin point bone tenderness
X-rays normal early, bone scan or MRI helpful |
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What are the featuresof parvovirus arthritis?
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-Painful, swollen joints of feet and hands
-Bright red "slapped cheeks" -Adolescence Rash and arthritis due to immunological rxn, not infection itself |
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What are the features of acute rheumatic fever?
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-2 weeks after Gp A strep (sore throat and fever)
-Can get arthritis without carditis -Responds well to NSAIDs -Major disease: Subcut nodules Pancarditis Arthritis Chorea Erythema marginatum |
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What are the features of post-infectious/reactive arthritis?
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-Arthritis 1-3 weeks after infection at another site
-Joint fluid sterile -Gp A strep or enteric (e.g. Salmonella) |
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What are the features of acute rheumatic fever?
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-2 weeks after sore throat and fever (gp A strep)
-Can get arthritis without anyother features SPACE -Subcut nodules -Pancarditis -Arthritis -Chorea -Erythema marginatum -Responds well to NSAIDs |
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Which malignancies can have arthritis as a component?
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Systemic: leukaemia, lymphoma and neuroblastoma
Local: osteoid osteoma, eosinophillic granuloma, sarcoma |
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What symptoms would make you think of malignancy?
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-Fever, weight loss
-Pain >> physical findings -Night pain -Hepatosplenomegaly -Lymphadenopathy -Anaemia -Metaphyseal lucency |
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What are some paediatric overuse syndromes?
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Little leaguer's elbow, swimmer's shoulder, avascular necrosis of the femoral head, slipped capital femoral epiphysis
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What is hip pain usually in ages 2-6?
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Transient synovitis
-May follow viral infection -Benign course -Normal x-ray -Slight effusion on u/s |
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What is hip pain usually in ages 4-10?
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Legg-Perthe's
-Avascular necrosis of the femoral head -More common in boys -Decreased ROM (red flag) -X-ray: sclerosis, loss of height in femoral head |
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What is hip pain usually in ages 10-14?
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Slipped capital femoral epiphysis
-Older boys, obese -Stand with leg slightly externally rotated -Fracture through growth plate |
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What are the features of growing pains?
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-No relation to growth
-Age 3-10 -Usually limited to calf, thigh, shins -Occurs at night (fine next morning) -Normal physical exam and tests |
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What are the types of JIA and what proportions of patients are in each?
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- Systemic arthritis (e.g. Still's disease): 10%
- Oligoarticular arthritis (<4 joints) 50% - Polyarthritis (>4 joints) 30% - Enthesitis related - Psoriatic arthritis - Unclassified |
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What are the features of systemic JIA?
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M=F
- Fever (spikes irregularly but returns to normal between spikes) - Rash (salmon pink that comes and goes) - Arthritis - Hepatosplenomegaly - Lymphadenopathy - Serositis (pericarditis) - Anaemia, high ESR, CRP, platelets |
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What are the features of oligoarticular JIA?
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- Age < 5 years
- Girls > boys - Large joints (knee most common) - ANA =ve in 80% |
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What are the complications associated with oligoarticular JIA?
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- Knee flexion contracture
- Quadriceps atrophy - Leg-length discrepancy - Uveitis (in 20%, ass'd with +ve ANA, assymptomatic but if untreated blindness in 2-3%. Does not parallel disease course so screen every 3-4 months) |
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What are the features of RF-negative polyarticular JIA?
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- Young girls > boys
- Small and large joints, neck, TMJs - Uveitis in 10% - Cervical spine arthritis - Growth disturbance (small jaw) |
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What are the features of RF-positive polyarticular JIA?
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- Older girls
- Symmetrical large and small joint arthritis - Rheumatoid nodules over pressure points in 30% - ANA may be +ve |
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What are the features on seronegative spondyloarthropathies?
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- Older boys >> girls
- PHx - Peripheral and axial arthritis - Absent ANA and RF - HLA B27 +ve - Enthesitis |
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What is the histologic diagnosis of Henoch-Schonlein purpura?
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Leukocytoclastic vasculitis
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What is Henoch-Schonlein purpura?
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- Small vessel vasculitis
- Affects skin, joints, GI tract, kidneys - Acute morbidity from GI complications (bleeding, intusseception) - Chronic morbidity related to end-stage renal disease - Can get acute scrotum, penis and abdomen |
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What are the classification criteria for Henoch-Schonlein purpura?
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Must have 2/4 of:
- Palpable purpura - Age <20 at onset - Bowel angina (after meals) - Granulocytes in walls of arterioles or venules on biopsy |
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What are the features of juvenile dermatomyositis?
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- Not related to malignancy
- Bright signal on MRI - Muscle weakness - Dilated capillary loops at the base of the fingernails - Gottren's papules (on knuckles) |
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What are the features of localised scleroderma?
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- Bands of thickened skin that run down a limb
- Can cause significant limitation of motion - Patches on skin |
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What are the features of SLE?
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- Butterfly rash on nasolabial folds
- Palatial ulceration - +/- vasculitis (immune deposits) - weight loss, night sweats, lethargy common |
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What is the epidemiology of SLE?
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- 20% of all cases commence at age <18 years
- Commoner in blacks, hispanics and asians - F:M 4.5:1 |
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What is the 6 step asthma management plan?
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1. Assess severity
2. Achieve best lung function 3. Maintain best lung function (triggers) 4. Maintain best lung function (meds) 5. Develop an asthma action plan 6. Educate and review |
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What are the features of mild, moderate and severe asthma?
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Pulse
- Mild <100 - Moderate 100-200 - Severe >200 SaO2 - Mild >94% - Moderate 90-94% - Severe <90% Central syanosis in severe only |
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What is Ipratropium (atrovent)?
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An anticholinergic drug. It blocks the muscarinic cholinergic receptors in the smooth muscles of the bronchi in the lungs
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Failing salbutamol and itrapropium, what are the next steps in acute asthma management?
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- IV bolus or infusion of salbutamol
- Magnesium sulphate bolus (a smooth muscle relaxant) - Aminophylline (loading and infusion) rarely used - Anaesthetic agents and muscle relaxants - CPAP - Intubation and ventillation |
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How is acute asthma therapy reduced?
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- "stretch" ventolin
- Wean O2 |
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What is described in a reducing medication plan?
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- Covers 3-5 days
- # of puffs and frequency of reliever - Oral steroid doses (mls) - Time until reviewed by GP |
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What are the different intervals of paediatric asthma (early morning/night cough, missing school, exercise symptoms)?
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- Infrequent intermittant (75%)
- Frequent intermittant (20%) - Persistent (mild, mod, severe) 5% |
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At what mental age can spirometry be performed?
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4-6 years
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What are some questions to ask in the assessment of asthma severity?
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- How often is sleep disturbed due to asthma?
- Is reliever used on waking? - Does asthma limit exercise? - How often in reliever used? - How long does the reliever last? - How much school has your chils missed due to asthma? |
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What investigations should be done for asthma?
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- Spirometry if old enough
- Possibly skin prick testing - Chest x-ray possibly if 1st presentation |
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What is contained in an asthma action plan?
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- Regular use of preventer
- How to increase reliever in response to symptoms - How to access medical care Evidence: improved adherence, decreased hospitalisation |
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What is the commonest cause of death and disability in the paediatric population?
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Trauma. Blunt injury commonly.
Falls and sporting injuries are commonest followed by MVAs Home is the commonest place of injury |
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What has brought about the decreased deaths from trauma?
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Prevention
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What is different about children in trauma?
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- Relatively bigger heads and organs
- Bones pliable (intrathoracic injury without fracture) - Refuse to communicate when injured - Small child: abdo injury in MVA - Non-compliance and peer pressure re: safety devices |
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What are the airway considerations in a traumatised child?
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- Big occiput (put blanket under shoulders to avoid flexing head, or used paeds spinal board)
- Short neck - Loose soft tissue swells a lot when burned - Short trachea (tube often inserted too far) - Crico-thyroidotomy difficult due to small membrane (if no other options use a needle and high pressure O2 but only works for 15min due to hypercarbia) |
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What do you need to consider in the breathing of a traumatised child?
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- Child's chest wall is thinner: difficult to localise added sounds
- Ribs more horizontal in younger children (less chest expansion) - Crying: air filled stomach pushes up on diaphragm - Infant RR 40-60/min - Tidal volume 7-10mL/kg |
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What do you need to consider in the circulation of a traumatised child?
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- Early signs of shock when ~1/4 blood loss (tachycardia)
- Shock can mimic head injury - Pulse pressure initially narrows, then widens late - Hypotension = 45% loss of volume |
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What Rx do you give when a child is tachcardic after trauma?
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- Give bolus of 20mL/kg
- Don't overresuscitate in penetrating injury - Start with normal saline or Hartmann's - Give 3 x crystalloid then blood - Remember BSL in infants |
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What are the circulatory parameters in a child?
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- Blood volume 80mL/kg
- Systolic BP = 80 + 2x age in years - Diastolic = 2/3 x systolic |
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What are the disability considerations in traumatised children?
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- Difficult to assess in children
- AVPU used (if P, GCS = 9) - Children have thin cranial bones |
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What does the secondary survey comprise of in traumatised children?
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- Head to foot exam
- AMPLE Hx (allergies, medications, past MHx, last meal, events surrounding) - Imaging (additional apart from trauma series) - Consider transfer early |
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What is a Chance fracture?
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- Flexion fracture of the spine
- Usually T12-L2 - Check for hollow viscus injury if present |
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What should be considered in abdo trauma in children?
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- Usually blunt
- Children have thin abdo wall and an abdominal bladder - FAST: fluid +stable = CT, fluid + unstable = surgery - Spare spleen if stable - Handlebar injuries surprisingly serious (and seatbelt) |
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What should be considered in head trauma in children
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- Commonest cause of death
- Maintain ABCs: most important in preventing secondary injury |
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What should be considered in chest trauma in children?
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- Uncommon
- Most invasive Rx is likely to be a chest train - Consider lung contusion in the absence of fracture |
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What is the epidemiology of acute respiratory infections?
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- 50% of all illnesess in age <5
- 30% in 5-12 - 95% of these URTIs - LRTI: early life and boys |
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What are some URTIs children can get?
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- Colds/coryza
- Pharyngitis - Tonsillitis - Otitis media - Sinusitis |
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What are some LRTIs children can get?
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- Laryngo tracheobronchitis
- Epiglottitis - Acute bronchitis - Acute bronchiolitis - Pneumonia |
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What are the viral aetiologies of ARIs in children?
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- 90%
- Rhinovirus - Respiratory syncitial virus - Parainfluenza types 1, 2 & 3 - Influenza types a & b - Adenovirus - Metapneumovirus |
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What are the bacterial aetiologies of ARIs in children?
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- 10%
- Beta-haemolytic streptococcus - Streptococcus pneumoniae - Haemophillus influenzae - Staphlococcus aureus - Mycoplasma pneumoniae, Chlamydia, pneumoniae, Leigonella |
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What are the red flags for resuscitation in children?
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- Purpuric rash
- Bulging fontanelle - Biphasic stridor - High-pitched scream - Bile-stained vomit - Persistent tachycardia - Grunting respiration |
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What is the ABCD of recognising serious illness early in children?
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A: airway, alertness, activity
B: breathing difficulty C: circulatory impairment D: daily fluid balance (input & output) |
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What id decorticate posturing and where is the lesion?
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- Flexing of arms and wrists
- Suggests lesion is above the brainstem |
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What id decerebrate posturing and where is the lesion?
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- Extension at elbows and flexion at wrists
- Suggests midbrain or pontine lesion |
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What are the signs of increased effort of breathing?
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- Grunting
- Audible inspiratory/expiratory noises - Nasal flare - Recession - Accessory muscle use - Respiratory rate - Head bobbing |