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3 Cards in this Set

  • Front
  • Back
Levodopa
(L-Dopa)
precursor to the neurotransmitters dopamine.
passes the BBB.
counteracts deficiency of Dopamine in the basal gng. (=parkinson).
SidEf- involuntary movement, on-off effect, nausea, anxiety, postural HypoTens & psychotic symptoms.
Carbidopa
given together with L-Dopa.
doesn't pass the BBB.
inhibits peripheral metabolism of levodopa and its effect on the periphery and increases the L-Dopa t1\2.
Entacapone
A COMT inhibitor.
increases the t1\2 of dopamine (inhibits dopamine metabolism.
SidEf- involuntary movements.