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37 Cards in this Set

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  • Back
during what phase is liver tissue enhancement most prominent
portal venous phase
what are some examples of fibrous tissue that may occur in the liver
cirrhosis
capsule
Central scar
Confluent fibrosis
cholangiocarcinoma
when does fibrous tissue tend to enhance
after a delay
does hepatocellular carcinoma tend to have solitary or multiple lesions
it depends if the patient cirrhosis than they will most likely have multiple nodules however if the patient does not have cirrhosis than HCC will likely be solitary
what percent of a hccarcinoma has a capsule
26%
What signal intensity are HCC typicaly? What determines how bright they will be on T2? Do all HCC have change in SI on T2 or T1? what percent of hepatocellular carcinoma has a portion with high T-1 signal?
increased SI on T2

No a lot of HCC have no change of SI at all and you will only pick them up on post contrast
the more dysplastic the great the brighntess on T1

approximately 50%
what percent of patients that have cirrhosis will have a central star in their hepatocellular carcinoma lesion
only 6%, however if the patient does not have cirrhosis there is a 50% chance they will have a central star
what is the most common feature of hepatocellular carcinoma
is well circumscribed
what is a common type of hepatocellular carcinoma that occurs in non-cirrhotic patients
fibrolamellar hepatocellular carcinoma
what are some characteristics of fibrolamellar hepatocellular carcinoma
it's rare, occurs in noncirrhotics, most of the time encapsulated, 50% of the time has a central star
what are some liver lesions that may have a central star
hepatic adenomas, hepatocellular carcinoma, focal nodular hyperplasia, large hemangiomas
what are some examples of hypervascular metastasis
carcinoid, islet cell tumors, pheochromocytoma, thyroid carcinoma, renal cell carcinoma, and possibly but not always breasts and melanoma
what are some examples of cystic metastasis of the liver
ovarian carcinoma, small cell lung carcinoma, choriocarcinoma, endometerial carcinoma, gastric carcinoma, sarcoma, GIST
what is GIST more hypervascular before or after gleevac
after
what are some types of a hepatic metastasis that may become calcified
mucinous adenocarcinoma;
ovarian, colon, rectum, stomach, breast
can a mucinous producing tumor be cold on pet
yes
what are some examples of lesions that will be hyperintense on T-1
lesions that may contained fat such as hepatic adenomas, hepatocellular carcinoma. Also; melanoma, hemorrhagic tumors, ( hepatic adenomas, hepatocellular carcinoma, Mets) cyst with protein/hemorrhage
what are some causes of the T2 lightbulb sign on MRI
hemangioma, cyst, hypervascular meds, HCC but this one is rare
what are some examples of ringed lesions of the liver
hematoma, hepatocellular carcinoma, hepatic adenoma, metastasis, inflammatory cyst such as Candida
what is the liver parenchyma made up of in diffuse liver disease of cirrhosis
fat, fibrosis, regenerating nodules
what are some causes of diffuse liver disease involving fat deposition
obesity (NASH) hepatic toxins, diabetes, TPN, malnutrition
what are some of the common locations of fat deposition in the liver
periligamentous, pericholecystic, perihilar, sub capsular,
what are some of the common locations of fat deposition in the liver
periligamentous, pericholecystic, perihilar, sub capsular,
why are some regions of the liver areas that commonly retain fat
this is due to abberant venous drainage
does the perihilar region always contain fat first
no this could be a fat sparing area or an area of focal fat collection
what are some causes of hepatic deposition of iron
hemochromatosis, intravascular hemolysis, cirrhosis, or because of transfusions
what are some of the consequences of iron overload
cardiomyopathy, hepatocellular carcinoma and diabetes
what happens to the liver when there is too much iron
it becomes bright on CT
what signal intensity is the liver on T2 \when there is iron deposition
little signal intensity/dark
what is a differential diagnosis for hyper attenuating lesions go in the liver
iron deposition
chemotherapy
glycogen storage disease
amiodarone
thorotrast
arsenic poisoning
what is it called when this obstruction of the hepatic venules
venocclusive disease no
what are two locations where Budd-chiari disease tends to occur
large hepatic veins and suprahe nopatic will inferior vena cava
what are some of the common causes of bud Chiari syndrome
idiopathic
birth-control
trauma polycythemia vera
what are the perfusion patterns primary sclerosing cholangitis and bud chiari syndrome
Central to peripheral
what is the differential diagnosis of diffuse metastasis to the liver
small cell carcinoma of the lung
melanoma
breast carcinoma
endocrine tumors
What enhances during the arterial phase in FNH
the non- central scar portion
What happens to the central scar during the delayed phase
it enhances while the peripheral part of the lesion washes out and becomes isodense