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53 Cards in this Set
- Front
- Back
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Name pathologies of Free Radical Injury
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1. Retinopathy of prematurity
2. Bronchopulmonary dysplasia 3. CCl4 -> liver necrosis (fatty change) 4. Acetaminophen 5. Fe overload 6. Reperfusion injury |
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Granulomatous diseases
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1. TB
2. Fungal infections (histo, blasto) 3. Treponema pallidum (syph) gumma 4. M. leprae (leprosy) 5. Bartonella henselae (cat scratch) 6. Sarcoid 7. Crohn's 8. Berylliosis 9. Listeria 10. Foreign bodies 11. Wegener's 12. CGD |
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Diseases w/ Decreases ESR
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1. Sickle cell (altered shape)
2. Polycytemia (too many) 3. CHF (unknown) |
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Diseases w/ INcreased ESR
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1. Infections (esp osteomyelitis)
2. Inflammation (temporal arteritis) 3. Cancer 4. Pregnancy 5. SLE |
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Bence Jones
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AL, light chains MM
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Secondary
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AA, SAA
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Senile cardiac
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Transthyretin , AF
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DM2
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Amylin, AE
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Medullary carcinoma of the thyroid
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A-CAL, Calcitonin
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Alzeimer's
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B-amyloid, Amyloid precursor protein (APP)
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Dialysis-associated
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B2-microglobulin, MHC class I proteins
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AL
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Ig kappa light chains MM, Bence Jones
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AA
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Serum amyloid-associated (SAA) protein (chronic inflammaotyr disease), Secondary - AA = acute phase reactatn
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Transthyretin
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AF, senile cardiac
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Amylin
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AE, T2DM
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A-CAL
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calcitonin, medullary carcinoma of the thyroid
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B-amyloid
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Amyloid precursor protein, APP, Alzheimers
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B2-microglobulin
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MHC 1 proteins, Dialysis associated
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Ig light chains
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Bence jones, AL
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SAA
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Serum amyloid associated protien (chronic inflammatory disease), AA, Secondary
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AF
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Transthyretin, SEnile cardiac
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AE
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Amylin, T2MD
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Calcitonin
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A-CAL, medullary carcinoma of the thyroid
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Amyloid precursour protein (APP)
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B-Amyloid, Alzheimers
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MHC class I proteins
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B2-microglobulin, Dialysis asociated
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PSA
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prostate carcinoma
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Prostatic acid phosphatase
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Prostate carcinoma
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CEA
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CRC, pancreatic cancer, gastric, breast, and thyroid medullary carinomas (carcinoembryonic Ag) Very nonspecific
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AFP
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HCC, yolk sac (endodermal sinus)
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B-hcG
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hydatidiform moles, choriocarcinoma, and gestational trophoblastic tumors
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CA-125
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Ovarian, maligant epithelial cancers
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S-100
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Melanoma, neural tumors, astrocytomas (NC orign)
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Alkaline phosphatase (Alk Phos)
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Mets to bone, obstructive biliary disease, Paget's disease of bone
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Bombesin
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Neuroblastoma, lung nad gastric cancer
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TRAP
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Tartrate-resistant acid phosphatase, Hairy Cell leukmia
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CA-19-9
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Pancreatic adenocarcinoma
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Calcitonin
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Thyroid medullar carcinoma
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Aflatoxin (aspergillus)
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Liver - HCC
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Vinyl Chloride
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Liver - Angiosarcoma
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CCl4
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Liver - Centriolobular necrosis, fatty change
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Nitrosamines (smoked foods)
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Stomach - Gatric cancer
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Cigarette smoke
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Larynx - SCC
Lung - SCC and small cell carcinoma Kidney - RCC Bladder - Transitional cell carcinoma |
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Asbestos
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Lung - Mesothelioma and bronchogenic carcinoma
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Arsenic
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Skin - SCC
Liver - Angiosarcoma |
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Naphthalene (aniline) dyes
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Bladder - Transitional cell carcinoma
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Alkylating agents
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Blood - Leukemia
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Radon
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Lung - lung cancer
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Angiocarcinoma
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Vinyl chloride
Arsenic |
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Psammoma bodies
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1. Papillary adenocarcinoma of thyroid
2. Serous cystadenocarcinoma of ovary 3. Meningioma 4. Malignant Mesothelioma |
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PSaMMoma
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P = papillary (thyroid)
S = Serous (ovary) M = Meningioma M = Mesothelioma |
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Mets to Brain
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Lung > breast > kidney > skin (melanoma)
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Mets to liver
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Colon > stomach > pancreas > breast > lung
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Mets to Bone
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Prostate = Breast > lung > thyroid = testes
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