pathophys endocrinology Flash Cards

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Title: pathophys endocrinology
Description: thyroid and endocrine
Number of Cards: 10
Save Count: 0
Author: nikki.amirlatifi14
Created: 2011-12-07
Tags: endocrine pathophys thyroid
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    • Question
    • Answer
    • Side 3
    • the upper margin of the thyroid isthmus is just below what structure?
    • cricoid cartilage
    • How much does the normal thyroid gland weigh?
    • 20 g.
    • Which embryonic tissue is the thyroid derived from?
    • embryonic endoderm
    • Thyroid follicles consist of what? (3)
    • follicular cells (secrete T4 and 53), colloid (jellylike substance inside follicle containing thyroglobulin), parafollicular cells (outside follicles)
    • What do parafollicular cells secrete?
    • calcitonin
    • Conversion of T4 to T3 occurs in what tissues?
    • kidney, liver
    • rT3...what is it?
    • reverse t3, nearly all produced extrathyroidally, more rapid metabolic clearance, little or no biologic activity
    • What are the 3 proteins T3 and T4 bind to in circulation?
    • 70% to TBG, 10% T4 and very little T3 to transthyretin, 25% T3 and 15% T4 to albumin
    • How are T3 and T4 excreted?
    • form glucoronide conjugates that are excreted via bile into feces
    • What is calorigenesis?
    • Basal metabolic rate