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16 Cards in this Set
- Front
- Back
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This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention
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Bethanechol
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Only direct acting agent that is very lipid soluble and used in glaucoma
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Pilocarpine
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This agent used to treat dry mouth in Sjögren's syndrome
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Cevimeline
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Indirect-Acting ACh Agonist, alcohol, short DOA and used in diagnosis of myasthenia gravis
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Edrophonium
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Carbamate with intermediate action, used for+A1170 postoperative and neurogenic ileus and urinary retention
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Neostigmine
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Treatment of atropine overdose and glaucoma (because lipid soluable). Enters the CNS rapidly and has a stimulant effect, which may lead to convulsions
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Physostigmine
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Treatment of myasthenia gravis
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Pyridostigmine
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Antiglaucoma organophosphate
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Echothiophate
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Associated with an increased incidence of cataracts in patients treated for glaucoma
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Long acting cholinesterase inhibitors
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Scabicide organophosphate
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Malathion
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Organophosphate anthelmintic agent with long DOA
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Metrifonate
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Toxicity of organophosphate:
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DUMBELSS (diarrhea, urination, miosis, bronchoconstriction, excitation of skeletal muscle and CNS, lacrimation, salivation, and sweating)
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The most frequent cause of acute deaths in cholinesterase inhibitor toxicity
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Respiratory failure
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The most toxic organophosphate
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Parathion
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Treatment of choice for organophosphate overdose
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Atropine
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This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure
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Pralidoxime
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