pharm ex 3 part 4

tx for alochol addiction

opoid antagonist that reduces alochol cravings

NMDA receport antagonist to prevent relapse from alcohol

depednnce, addiction RARE, low dose- vom, burred vision, anorexia, tremor, high dose dependence- seizure, psychosis, depression , low dose withrdawam- diazepam, swtich to long acting and reduce dose, high dose- stop other drug abuse then long acting

same as benzo

partial agonsit at nicotinic receptor in CNS, tx of nicotininc addiction

for nicotnic additioction, sustained release

STRONG tolerance and dependence , withdrawal- dsyphoria, lacrimation, rhinorriea and yawning , withdrawal- methadone, buprenorphine

presynaptic alpha 2 agonist used for tx of opoid withdral

therapeutic- dronabinol for anorxia and nausea, toliderance and dependcne, ACTION- eurphora, short term memorm impaired, impairs motor skiss, munchies, AE- increased HR, red conjunctiva, toxic psychosis

5HT2 receptors, NO ADDICTION and NO WITHDRAWAL, bad trips, severe agitation

non competive antagonist at NMDA rof glutamte receptor, high doses inhibts DA uptake, dissociateve anesthesia and analgesia, tolerance after contineud use

empathy and intimcy without impairing intellectual capacities, increases serotonin, widrawl- depression

euphoria and analgesia and loss of convious, asyphia and death if 100%

gasoline, paint thinner, exhilization and light headeed, AE- CA, cardiotoxicity, neuropathies, hepatoxcity

amyl nitrite and butyl nitrite, enhance rekection

body building atheletes

general anzesia, IRRITATES AIRWAYS, special dispending due to LOW BP, decreases vascular resistance, increases HR and symp stimulation at high concentrations

pediatric anestheia, broncodliation, releases fluride-->nephrotoxic

good analgenis and mucle relaxant but PUNGET, high concetration- TWITCHING and TONIC CLOSING, do NOT USR WITH SEIZURE diodrders, CI in rneal failure pts

less CV efects than halotahate, hypotenion, cornoary vasodilater, good for PTS WITH IHD

weak analgesic, causes myocardial depression, decreased CO and decreased BP, causes hepatoxicity

nephrotic potential due to fluroride released during metnabolism, general anestheic

induction of anethesia for short surgical prcesures, hepatic met requires, short acting barbituates

benzos used premedication, intrapo sedation

accelerate recovery from benzo

general anestheic, increase chest wall rigidity, post op resperiatory dperession give nalaxone, when becomes with neuroleptic can lead to neuroleptic analagesia(F),

combo with fentnayl will lead to neuroleptic analgesia and if u give NO2 can be neurlept anesthesia

IV anestic, antiemetic, no alageisa, metablized in liber, HYPOTENSION, NEGATIVE IONOTROPE

slight hypotenion, vomiting and nausea, general anesthetic, no effect on HR, no analgesic effects, adrenocortical supression via inhbiting steroidogenesis

dissociated anesthesia, amensia, loss of consiouness, NMDA receptor blockade, emergence phenomena- disoritention, sensory and perceptual illusions

adjuct for general surgery

adjuct for general surgery

adjuct for general surgery , antiemetic

adjuct, amnesic effects, prevent salication and bronchial secreiton, protenct hrt from bradycarida

local anestheci , opthalmic anethesia, part of TAC(tetraaine, adrenaline and cocaine) , suturing small cots, EMLA uses inteasd due to toxicity , CARDIOTOXIC, vasoconstrictive

local anestheci, infiltration anehtsia and dental, dx nerve blocks, short acting- 2-chlorproaicne- obstretic anesthetic

local anestheci , long acting, highly potenti, high hhydroibicity, spinal and topical anethesia

local anestheci

local anestheci , peripheral nerve block, epidural, spinal, topica, class I antiarrthmic , rapid onset

local anestheci , long duration of action, potent, HIGH CARDIOTXOCITY, isomer levobupivaicain less toxic

local anestheci, can use WITHOUT A VANCONSTRICER, METHEMOGLOBINEMIA

local anestheci , less cardiotxic than bupivicain with sim effects

non depol blocker

non depol blocker, inactivated by hydorlysis of non specific plasma esteras, SAFE inrenal failure pts, LAUDANOSINE METABOLITE that can lead to hypotenin and seixzures

non depol blockers, seteroioser of atraciruim that doesn’t form laudnne, pressured to atraciruim

non depol benzylisoquinoline, long acting

non depol blocer, short duration of action, hydrolysis by plasma butrylcholneratasee devactivates, NOT DEP IN LIVER OR KIDNEY

non depol blocker, blocks cadiac M2, causes tachycardia, not usually a problem

non depol blocerks, ammonio steroid , long acting , intermediate acting

non depol blocker, aminio sterid

depol blockers, short duration, hydrosis by liver and plasma butrylcholerase, if abd varial of butryolcholerase could lead to long effects

spasmolytic , faciliates action of GABA at GABAa receptors

spasmolytic, GABAb agonist

spasmolytic, alpha 2 agonist

spasmolytic, increases GABA release

spasmotlyci, GABA a and GABAb agonist

imhbitory amino acid, passes BBB, spmasmolytic

tx of ALS, inhibits of glutamergic transmission in CNS

interferes with release Ca by binding to ryanodine receptor, used in malig hyperterhmia

generalzied spastic seizures, cerebral palsy

tx for acute msucle spasm, stong antimuscarininc, sedation and confusion its pts with visual hallicnation