- Shuffle
Toggle OnToggle Off
- Alphabetize
Toggle OnToggle Off
- Front First
Toggle OnToggle Off
- Both Sides
Toggle OnToggle Off
Front
How to study your flashcards.
Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key
Up/Down arrow keys: Flip the card between the front and back.down keyup key
H key: Show hint (3rd side).h key
PLAY BUTTON
PLAY BUTTON
20 Cards in this Set
- Front
- Back
|
Imipramine
|
TCA: inhibits both 5HT & NE
|
|
Chlorimipramine
|
TCA: inhibits 5HT
CHLORIMIPRAMINE YOU WON'T WANT TO CLEAN PUT DOWN THE CHLORINE CHLORIMIPRAMINE |
|
Desipramine
|
TCA: inhibits NE
|
|
TCAs: Onset? Absorbed? properties? metab? interactions?
|
Onset over days; well absorbed; lipophilic; accumulate in tissues; metab by liver, cyp; potential for many interactions
|
|
TCA SE
|
antimuscarinic ie dry mouth, constipation, blurred vision
anti-alpha 1 adrenergic (hypotension, weight gain, sedation, sexual dysfunction) mania in BP low safety factor (OD) |
|
SSRI, list names
|
Fluoxetine, citalopram, fluvoxamine, paroxetine, sertraline
|
|
SNRI, list names
|
venlafaxine, dualoxetine, milnacipran (2 oxs in Milan & Venice fax)
|
|
Vilazodone
|
SSRI w/ partial agonist at 5 HT
|
|
SSRI/SNRI considerations
|
slow onset (days)
effect can be augmented (albeit modestly) by second generation antipsychotic (but w/ increase in adverse effects) |
|
SSRI/SNRI absorption
|
generally well absorbed, variable plasma protein binding, metabolized by hepatic, sometimes active metabolite
|
|
SSRI/SNRI SE
|
much less than TCA, dizziness, jittery, insomnia, nausea, diarrhea, fatigue, sex dys
|
|
List MAOI
|
selegeline, phenelzine, tranycypromine, moclobemide
(SELENA EATS PHENEL WITH TRANYS AND MO CLOBBERS HER) |
|
SELEGILINE
|
preferential inhibitor of MAO-B (mao A has a bigger effect on brain, less likely to have"cheese effect".... which is preferential for maoA? Moclobemide)
|
|
Moclobemide
|
preferential inhibitor of MAO-A
|
|
phenelsine and tranylcypromine
|
inhibit MAOA & MAOb
|
|
Other antidepressants, list
|
Nefazone, Trazodone, Bupropion, Mirtazapine (NEFROTITI TRIED to BURP in the MIRROR)
|
|
What to use with bipolar? ?
|
Lithium (many SE, monitor blood levels, can be changed with increased/decreased Na+ absorption): Risk of suicide lower
Also: Anticonvulsants (Lamotingine, carbamazapine, valproate---> RAY LAMONTANGNAE'S CAR has a V-8 and CONVULSES) Atypical antipsychotics perhaps for acute manic phase (queen oleans risks unzipping and ripping one) |
|
what to use with panic disorders?
|
SSRIs > TCA/MAOI > benzos (alazapram, clonazapam) for rapid relief
|
|
what to use in OCD?
|
chlorimipramine (TCA) > SSRIs > MAOIs
Interestingly, NE reuptake inhibitors are not effective in OCD |
|
what to use in excessive day time sleepiness and narcolepsy?
|
modafinil
sodium oxybate |
