• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

image

PLAY BUTTON

image

PLAY BUTTON

image

Progress

1/11

Click to flip

Card Range To Study

through

11 Cards in this Set

  • Front
  • Back
Diphenhydramine
Dimenhydrinate
Chlorpheniramine
MOA: Reversible H1 receptor inhibitor (FIRST generation)
Uses: Allergy, motion sickness, sleep aid
Toxicity: Sedation, Antimuscarinic, anti-alpha-adrenergic
Loratadine
Fexofenadine
Desloratadine
Ceterizine
MOA: Reversible inhibitor of H1 receptor (SECOND generation)
Uses: allergy
Toxicity: less sedating than 1st gen b/c decreased CNS entry
Isoproterenol
nonspecific beta-agonist; relaxes bronchial sm. muscle through beta-2
adverse rxn: tachycardia (beta-1)
Albuterol
beta-2 agonist
use: acute exacerbation
Salmeterol
beta-2 agonist
use: prophylaxis (long-acting)
toxicity: tremor, arrhythmia
Theophylline (methylxanthines)
phosphodiesterase inhibitor, decreasing cAMP hydrolysis --> bronchodilation
narrow therapeutic index (cardio and neurotoxic)
P-450 metabolism
Ipratropium
block muscarinic receptors (prevent bronchoconstriction)
use for COPD, asthma
Cromolyn
prevents mast cell release of mediators
use: asthma PPX
toxicities rare
Beclomethasone
Prednisone
inhibits synthesis of cytokines, inactivates NF-kappaB (tx factor for TNF-alpha)
use: 1st line for chronic asthma
Zileuton
5-lipoxygenase pathway inhibitor (blocks: arachidonic acid --> leukotriene)
Zafirlukast
Montelukast
block leukotriene receptors
use: good for ASA-induced asthma