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24 Cards in this Set
- Front
- Back
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What is synthroid?
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Most common synthetic T4 therapy
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What is Levothyroid?
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Most common synthetic T4 therapy
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What is the most common T4 therapy?
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Synthroid or levothryoid
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What is Liothyronine?
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Most common T3 therapy
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What is the most common T3 therapy?
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Liothyronine
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What is Liotrox?
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A synthetic T3/T4 combo
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What is the indication for Methimazole in pregnant women?
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It is a synthesis inhibitor that crosses the placental barrier, so it is contraindicated
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What is methimazole?
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A thyroid hormone synthesis inhibitor
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What is propylthiouracil (PTU)?
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a protype synthesis inhibitor
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which is more potent, propylthioruacil (PTU) or methimazole? longer half life.
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Methimazole is 10-50x more potent. Methimazole.
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What are thiocynate and perchlorate?
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Ionic inhibitors of iodide transport
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How might iodide be used therapeutically?
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High concentrations inhibit release of thyroid hormones
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What drug can be given in a smaller dose in smokers?
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thiocyanate
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What is Etidornate?
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A mineralization inhibitor biphosphate
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What is pamidronate?
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Biphosphate
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What are biphosphates used for?
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hypercalcemia, paget's diease, osteoporosis
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How do ionic inhibitors work? Name 2.
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Interfere with the concentration of iodide by the thyroid gland. Thiocyanate and perchlorate
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What is the Wolff-Chaikoff effect?
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Iodide inhibits the synthesis of iodotyrosine and iodotyronines.
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How do ionic inhibitors work? Name 2.
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Interfere with the concentration of iodide by the thyroid gland. Thiocyanate and perchlorate
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What is the Wolff-Chaikoff effect?
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Iodide inhibits the synthesis of iodotyrosine and iodotyronines.
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What is the MOA of bisphosphates?
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Inhibit bone resorption by repressing osteoclast function.
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What is the typical treatment regimen for osteoporosis?
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Physical Activity
Proper dietary calcium Vit D CT Bisphosphonates Thiazides |
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Why do you use thiazides in osteoporosis?
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Reduction of urinary calcium and limits bone loss in pts with hypercalciuria
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What is cibacalcin?
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Therapeutic Calcitonin
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