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8 Cards in this Set
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- Back
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What type of bacteria do the first generation of cephalosporins have the highest activity against?
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- gram-positive bacteria
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What is the name of a first-generation cephalosporin? generic and (trade) dose, ROA
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- cefadroxil (duricef)
- PO 500mg- 1g/d |
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What is the name of a second-gen cephalosporin? generic and (trade) dose, ROA
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- cefaclor (ceclor)
- Oral 125-500 mg/d |
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What is the name of third-gen cephalosporin? generic, (trade) dose, ROA
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- cefixime (suprax)
- Oral 100-400 mg/d |
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What is the name of a fourth-gen cephalosporin? generic, (trade), dose, ROA
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- cefepime (Maxipime)
- IM or IV 500mg-2g/d |
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What is the mechanism of action of Cephalosporins?
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- Cell wall similar to penicillin
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What are common adverse effects of Cephalosporins? (6)
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- pain
- nausea - vomiting - glossitis - diarrhea - ab pain (all GI) |
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What are the serious adverse effects of Cephalosporins? (3)
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- anaphylaxis, neutropenia, nephritis
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