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9 Cards in this Set
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If you increase the osmolarity by adding an immpermeable solute (ie mannitol), the ECF becomes hyperosmolal.
What happens to the cells in this solution? |
Water will move out of the cell, and the cell will shrink. The cell will shrink until the osmolality is the same.
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How will a cell react to hyperosmolal ECF to return to normal cell volume?
(short term) |
The shrinking cell will activate many transportersfor eg. Na-H exchanger. This increases the solute inside the cells and thus the water uptake. The cell will then return to normal volume.
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What happens to cells in a hypo-osmolal solution?
(short term) |
The cell will swell until osmolality is the same.
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How does a cell return to normal volume after swelling due to solution Hypo-osmolality?
(short term) |
The cell will activate solute efflux pathways. It activates K, Cl channels and they are effluxed out of the cell./
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What happens in to a cell in a long term hyperosmolality solution?
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The cell will accumulate organic solutes (osmolytes) inside the cell.
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Does hydrostatic pressure rise between the cell wall and interstitial space?
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No, b/c the sell membranes are not rigid.
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If the hydrostatic pressure in interstitial space rises what happens to the cell?
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The cell will compress until the intracellular hydrostatic pressure is the same as outside.
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What happens to a cell if a permeant solute (ie. Urea) is added to the solution?
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The solute will diffuse across the cell membrane until equilibrium is obtained.
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What contributes to the effective osmotic pressure?
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Only particles that are unable to pass thru the membrane.
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