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6 Cards in this Set
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etiology
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due to tissue factor release and/ or damaged epithelium>>>> clotting ( small thrombi) and continue consumption of procoagulants
---- secondary to retain of prodict of conception, postpartum hemorrhage, any cause of prolonged hemorrhage, malignancy, trauma or sepsis. other causative factors-- rhabdomyolysis, adenocarcinoma heat strokes sepsis!!!! tranfusion reaction, head trauma burns abraptio placenta amnionic fluid embolism snake bites pancreatitis |
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clinical
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bleeding from any possible site because it is consumptions of platelets and clotting factors
thrombosis is less common hemolysis is more often and can lead to renal failure confusion and jaundice |
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ds
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schistocytes
thrombocytopenia reticulocytosus decreased fibrinogen elevated PT elevated PTT increased d -dimers increasedfibrin split product level |
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tx
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1. treat undrelying disease
provide supportive therapy with transfusion of packed red blood cells, platelets FFP cryoprecipitate |
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if DIC develops intraoperatively what to do
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1. stop the surgery
treat DIC return to operation rrom when bleeding stops |
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what about heparin
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still contravesial-- may be used in the cases of acute thrombosis
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