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27 Cards in this Set
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What are the 4 main seronegative spondyloarthropathies?
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Ankylosing Spondylitis (AS)
Reiter's Syndrome (reactive arthritis) Psoriatic Arthritis Arthritis of Inflammatory Bowel Disease |
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seronegative spondyloarthropathies are associated with
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extraarticular manifestations
(psoriasis, iritis, aortic incompetence, apical pulmonary fibrosis) |
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what are the extraarticular manifestations of seronegative spondyloarthropathies?
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psoriasis, iritis, aortic incompetence, apical pulmonary fibrosis
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What are the genetic association for seronegative spondyloarthropathies?
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HLA B27 +ve but RF -ve
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Epidemiology of Ankylosing Spondylitis?
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Onset: late adolescent, early adulthood
Males >> Females White Genetic marker HLA-B27~ 90% |
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Triad of Reiter's Syndrome
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Conjunctivitis
Arthritis Nongonococcal urethritis |
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Epidemiology of Reiter's Syndrome?
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Males >> females
Organisms → Chlamydia, Campylobacter, Yersinia, Shigella, Salmonella White Associated with HIV |
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what is the prevalence of psoriatic arthritis in psoriasis?
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5-7%
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what is the M:F preponderance of psoriatic arthritis?
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M=F
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what is the age of onset of psoriatic arthritis?
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30-55 years
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What are the genetic marker for psoriatic arthritis?
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HLA-B27
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clinical presentation of psoriasis
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Psoriatic skin lesions—erythematous, silvery scales
Auspitz sign—gentle scraping of the lesions results in pinpoint bleeding extensor surfaces Nail pitting |
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Which conditions?
symmetrical small joint polyarthralgia |
RA
SLE |
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Which conditions?
asymmetrical small & large joint polyarthralgia |
psoriatic arthritis
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Which conditions?
asymmetrical lower limb polyarthralgia |
reactive arthritis
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Dactylitis (sausage digits) is present in
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psoriatic & reactive arthritis
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severity of polyarthralgia is best determined by
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duration of morning stiffness
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what extra-articular features are present in inflammatory spondyloarthropathy?
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iritis
inflammatory back pain asymmetrical lower limb arthritis |
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what extra-articular features are present in SLE?
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raynaud's
malar rash serositis proteinuria |
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what extra-articular features are present in psoriatic arthritis?
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scaly rash (psoriasis)
dactylitis nail pitting |
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what are the xray findings seen in OA?
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joint space narrowing
osteophytes subchondral sclerosis (increased bone formation around the joint) subchondral cyst |
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soft swellings are likely due to
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fluid
synovium |
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hard swellings are likely due to
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bone
tophi |
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CAUSES of carpal tunnel syndrome
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overuse / idiopathic
pregnancy & obesity RA & gout diabetes, hypothyroid, acromegaly amyloidosis |
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Ottawa Knee Rule:
A knee x-ray series is only required for knee injury patients with? |
age ≥ 55
isolated patella tenderness head of fibula tenderness inability to flex to 90° inability to bear weight immediately and for 4 steps (transfer weight twice) |
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Ottawa Ankle Rule:
An ankle x-ray series is only required if |
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Ottawa Ankle Rule:
A foot x-ray series is only required if |
there is any pain in the midfoot zone
+ bone tenderness at base of 5th metatarsal OR bone tenderness at navicular OR inability to bear weight both immediately & in ED |
