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8 Cards in this Set
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effective population size (Ne
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● the average number of individuals in a population that contribute genes to succeeding generations
● (formal) An ideal population of size N in which all parents have an equal expectation of being the parents of any progeny |
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Calculate effective population size
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Ne = (4Nc – 2)/(Vk + 2)
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loss of heterozygosity
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Ne = t /(Σ (1/Ni))
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effective population size
male to female |
Ne = 4NfNm/Nf + Nm
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ratio of effective to census size
Ne = Nc/(1 + F) |
Ne = Nc/(1 + F)
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Genetic estimates of Ne assume that all changes in allele frequencies are due to drift. Is this a good assumption? Why or why not?
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No.
–Most reliable requires genetic samples from two or more time periods separated by at least one generation –Look at variation in allele frequencies over time –Assumes all changes in allele frequencies are due to drift (not true) –As population becomes smaller and number of generations greater, more change in allele frequency expected from drift –Other methods account for migration |
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Why is Ne smaller for mtDNA than for nuclear DNA?
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•Individuals are haploid for mtDNA
•Maternally inherited •No recombination between mtDNA molecules •Drift and bottlenecks affect diversity at mtDNA more greatly than nuclear DNA •Loss of heterozygosity= 1/Nf |
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Is Ne a good indicator of loss of allelic diversity? Why or why not?
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No. Populations with the same rate of decline in heterozygosity may experience different rates in loss of allelic diversity
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