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19 Cards in this Set

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allergic rhinitis vs non-allergic
allergies have Abs and histamine release. Rhinitis from common cold has to be sympathetic NS-master NT = Ach
If common cold-better response from…
benadryl than from claritin (need an anticholinergic antihistamine)
general antihistamine cautions
angle-closure glaucoma (esp in anticholinergic antihistamines), urinary tract obstruction, dry mouth, tachycardia
What people are not tolerable to anticholinergic effects?
elderly
Highly anticholinergic drugs
sedating histamines and TCAs
Hydrozyzine used of the tx of…
anxiety (pre and post operatively), as a postoperative sedative, an antiprurtic, antiemetic, and for alcohol withdrawal sxs
hydroxyzine-not well tolerated in …
the elderly
cetirizine
metabolite of hydroxyzine
cetirizine indicated for
seasonal and perennial allergic rhinitis, urticaria
most sedating of the non-sedating antihistamines
cetirizine
do not use cetirizine in pts with…
hydroxyzine allergy
only antihistamine not metabolized by CYP 450 system
cetirizine
if allergic to antihistamine-probably allergic to…
the dye
antihistamine withdrawn from markey to multiple cases of QTc inerval prolongation/torsades
Terfenadine
antidote for torsades
magnesium
popularly marketed as a sleep aid
benadryl
benadryl uses
prevention of motion sickness and as an antitussive, tx of phenothiazine induced dystonic rxns (surge of Ach when given antipsychotic so hit them with an anticholinergic)
pseudoephedrine
alpha-1 agonist-will inc BP
nasal pseudoephedrine products
rebound congestion-do not use more than 3-5 dyas